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850890 UPS1

850890

UPS1

Ups1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Ups1p

研究结论

Date Results Publications
2019-04-06 11:35:00 Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins has been reported. 30850607
2016-04-23 11:40:00 crystal structure of Ups1-Mdm35 bound with a phosphatidic acid (PA) molecule at 2.0 A resolution; study reveals molecular basis of Ups1-Mdm35-mediated PA binding and transfer and sheds new light on mechanism of intramitochondrial lipid transport by MSF1/PRELI family proteins 26071601
2016-04-16 11:34:00 The Ups1-Mdm35 complex constitutes a single domain that has a deep pocket and flexible Omega-loop lid. A basic residue at the pocket bottom and the Omega-loop lid are important for phosphatidic acid extraction from the membrane following Ups1 binding. 26235513
2013-03-02 10:47:00 PS is transferred from the mitochondrial outer membrane to the inner membrane independently of Psd1p, Ups1p, and Ups2p and decarboxylated to PE by Psd1p in the inner membrane 23124206
2012-12-08 10:25:00 study identified Ups1 as a lipid transfer protein that can shuttle phosphatidic acid between mitochondrial membranes; lipid transfer required the dynamic assembly of Ups1 with Mdm35 and allowed conversion of phosphatidic acid to cardiolipin in the inner membrane 23042293

名称对应

Type IDs
Gene
UniProtKB-ID: UPS1_YEAST
UniprotKB: Q05776
UniParc: UPI000006984C
EMBL: U14913, BK006945
EnsemblGenome: YLR193C
KO: sce:YLR193C
Nucleutide sequences
EMBL-CDS: AAB67434.1, DAA09512.1
EnsemblGenome_TRS: YLR193C_mRNA
Protein sequencees
EnsemblGenome_PRO: YLR193C
RefSeq: NP_013294.1
Others
UniRef100: UniRef100_Q05776
UniRef90: UniRef90_Q05776
UniRef50: UniRef50_Q05776

全选

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研究热度

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