| Type | Description |
|---|---|
| Definition | NEDD8 ligase DCN1 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | The 1.9 A X-ray crystal structure of Dcn1 has an N-terminal ubiquitin-binding domain & a unique C-terminal domain. It does not require Cys for catalysis. It interacts with the Nedd8 E2 Ubc12 on a surface that overlaps the E1-binding site. | 18206966 |
| 2010-01-21 00:00:00 | Both in vivo and in vitro experiments indicate that Dcn1p does not inhibit deneddylation of Cdc53p by the COP9 signalosome, but greatly increases the kinetics of the neddylation reaction | 15988528 |
| 2010-01-21 00:00:00 | DCN-1 is a scaffold protein in a multisubunit neddylation E3 ligase complex | 17597076 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DCN1_YEAST
UniprotKB:
Q12395
UniParc:
UPI000006958A
EMBL:
U53877,
X91258,
Z73300,
BK006945,
X89514
EnsemblGenome:
YLR128W
KO:
sce:YLR128W
|
| Nucleutide sequences |
EMBL-CDS:
CAA61706.1,
CAA97697.1,
AAB82374.1,
CAA62639.1,
DAA09439.1
Gene_ORFName:
L3111
EnsemblGenome_TRS:
YLR128W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR128W
RefSeq:
NP_013229.1
|
| Others |
UniRef100:
UniRef100_Q12395
UniRef90:
UniRef90_Q12395
UniRef50:
UniRef50_Q12395
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33115720 |
G3 (Bethesda) Elsbeth Sanders , Phoebe A Nguyen , Cody M Rogers , Matthew L Bochman |
2020-12-03 | - |
| 29158339 |
G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese |
2018-01-04 | - |
| 28900268 |
Sci Rep Kristian Shulist , Eric Yen , Susanne Kaitna , Allen Leary , Alexandra Decterov , Debarun Gupta , Jackie Vogel |
2017-09-12 | - |
| 28754723 |
G3 (Bethesda) Vasso Makrantoni , Adam Ciesiolka , Conor Lawless , Josefin Fernius , Adele Marston , David Lydall , Michael J R Stark |
2017-09-07 | - |
| 27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
| 24470217 |
The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. G3 (Bethesda) David Atencio , Cassandra Barnes , Thomas M Duncan , Ian M Willis , Steven D Hanes |
2014-03-01 |
PEX34,
APA1,
GRX1,
RNQ1,
BUD3,
CWH43,
IMG2,
SSK22,
YFL051C,
FET5,
RPO41,
STE2,
AUA1,
VTC2,
MSH4,
DEG1,
QCR6,
SAP155,
BNA6,
HSP104,
RPL8B,
BRE2,
PSR2,
RPS0B,
YLR050C,
YLR053C,
OSW2,
RFU1,
CCW12,
YPS1,
DCN1,
ACF2,
SPE4,
STM1,
PCD1,
YLR173W,
TFS1,
YLR179C,
SWI6,
PEX13,
HCR1,
CRR1,
RSA3,
IRC20,
RCK2,
RED1,
NEJ1,
YLR297W,
PEX30,
VRP1,
RPL26A,
CIS1,
VPS38,
CCW14,
DUS4,
PAU4,
FUN19,
SNC1,
YAL065C,
FLC2,
HBT1,
YDL218W,
UGA3,
RPO21,
ARF2,
YDL109C,
IDP1,
RPS29B,
MBP1,
STP4,
NAT1,
DIA3,
RAD61,
NRG1,
YDR061W,
FMP16,
CPR1,
HOM2,
ARG82,
PLP1,
ATC1,
UPS3,
GTB1,
PMP3,
MRX10,
CPR5,
HNT2,
PMT7,
MCM21,
YSP2,
IRC3,
RQC1,
MRX8,
YDR338C,
YPS7,
CNL1,
CTS2,
ERD1,
SIP1
|
| 23583075 |
Principles of cotranslational ubiquitination and quality control at the ribosome. Mol. Cell Stefanie Duttler , Sebastian Pechmann , Judith Frydman |
2013-05-09 | - |
| 23332755 |
The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell Felix Willmund , Marta del Alamo , Sebastian Pechmann , Taotao Chen , Véronique Albanèse , Eric B Dammer , Junmin Peng , Judith Frydman |
2013-01-17 |
VAC17,
MIC10,
PRD1,
KAR4,
PBN1,
APA1,
POF1,
MGR1,
GLK1,
SRO9,
GFD2,
GRX1,
LSB5,
RNQ1,
HBN1,
DCC1,
GBP2,
ILV6,
STP22,
CDC10,
YCP4,
CIT2,
RVS161,
PGK1,
RHB1,
RIM1,
SYP1,
RPS14A,
RRP43,
YCR043C,
YCR051W,
THR4,
CTR86,
PWP2,
YIH1,
TAH1,
HCM1,
RSA4,
SOL2,
FUB1,
PAT1,
AHC2,
TRX3,
TUP1,
CSM1,
YCR090C,
MSH3,
YCR102C,
SNZ3,
SWP82,
RGD2,
SEC53,
OTU1,
ACT1,
YPT1,
TUB2,
MOB2,
RPL22B,
HAC1,
CAF16,
FRS2,
GAT1,
LPD1,
BLM10,
SEC4,
VTC2,
SPB4,
RPN11,
YFR006W,
YFH7,
IOC3,
ATG18,
LSB3,
HIS2,
CDC14,
RPL2A,
DUG1,
BNA6,
RMD8,
YMR31,
PRE4,
RET2,
RPN12,
HXK1,
IRC7,
GRC3,
RIX7,
YLL032C,
FRA1,
ISA1,
HSP104,
SSA2,
HIF1,
DPS1,
LMO1,
ORC3,
RTT109,
MHT1,
YLL058W
|
| 22271760 |
La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. RNA Luca Schenk , Dominik M Meinel , Katja Strässer , André P Gerber |
2012-03-01 |
YLR361C-A,
YDR003W-A,
SUS1,
YGR204C-A,
YJR112W-A,
YOR020W-A,
YIL002W-A,
YNL067W-B,
COA2,
YHL048C-A,
YHR175W-A,
PCC1,
VMA9,
MIC10,
PRD1,
PBN1,
SRO9,
GRX1,
LSB5,
MXR2,
STE50,
HIS4,
ILV6,
RER1,
MRPL32,
RVS161,
MAK31,
PMP1,
RHB1,
RIM1,
RPS14A,
RRP43,
YCR043C,
PER1,
BUD23,
ARE1,
YCR051W,
TAH1,
IMG2,
SSK22,
SOL2,
FUB1,
AHC2,
TRX3,
ABP1,
YCR090C,
HMRA1,
FMP32,
YPT1,
RPL22B,
GNA1,
HSP12,
WWM1,
LOC1,
YPI1,
IGD1,
HIS2,
RPL2A,
RPL29,
RSC8,
ERJ5,
KEG1,
DUG1,
YMR31,
EMC6,
COX17,
COF1,
LDB18,
RPL8B,
PAM18,
LOT6,
MEU1,
SED5,
RPL15A,
COX12,
IES3,
SPT8,
SHM2,
REX2,
ENV10,
SPC3,
FMP25,
ERG27,
SEN2,
AHP1,
SRN2,
YPS3,
DCN1,
ZRT2,
USB1,
RMP1,
SMD3,
RNH203,
ASP3-2,
RPS31,
UPS2,
DPH5,
TFS1,
YLR179C
|
| 21940857 |
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science Daniel C Scott , Julie K Monda , Eric J Bennett , J Wade Harper , Brenda A Schulman |
2011-11-04 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员