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8508 NIPSNAP1

8508

NIPSNAP1

nipsnap homolog 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition nipsnap homolog 1

研究结论

Date Results Publications
2020-01-11 10:45:00 NIPSNAP1 and NIPSNAP2 have a redundant function in mitophagy and are predominantly expressed in different tissues. 30982665
2017-06-10 10:58:00 identified mitochondrial proteins 4-nitrophenylphosphatase domain and non-neuronal synaptosomal associated protein 25-like protein homolog (NIP-SNAP)-1 and -2 as clarithromycin-binding proteins. Production of proinflammatory cytokines induced by lipopolysaccharides and Pam3-CSK4 in epithelial cell lines BEAS-2B and T24 were suppressed by knockdown of NIP-SNAP-1 or -2 27998764
2017-06-10 10:13:00 NIP-SNAP-1 and -2 localized in the mitochondrial inner membrane space, whereas HSP60 localized in the matrix. Expression levels of NIP-SNAP-1 and -2 in cells were decreased by knockdown of HSP60, but not HSP10. The findings indicate that HSP60 promotes folding and maintains the stability of NIP-SNAP-1 and -2. 28011268
2016-12-24 11:55:00 These results suggest that changes in NIPSNAP1 expression may contribute to the pathogenesis of inflammatory pain. 27030720
2015-05-16 10:52:00 Structural variants unique to the malignant cell line inactivated: gene NIPSNAP1, putative tumor suppressor that inhibits TRPV6, an anti-apoptotic oncogene implicated in prostate cancer progression. 23792589

名称对应

Type IDs
Gene
UniProtKB-ID: NIPS1_HUMAN, B4DQI7_HUMAN
UniprotKB: Q9BPW8, B4DQI7
UniParc: UPI00017A772E, UPI00001303FF
EMBL: AJ001258, CH471095, AK298816, AK314407, BC002371, BC006473
Ensembl: ENSG00000184117
KO: hsa:8508
Nucleutide sequences
EMBL-CDS: AAH06473.1, EAW59813.1, AAH02371.1, CAA04632.1, BAG37030.1, BAG60949.1
Ensembl_TRS: ENST00000216121
Protein sequencees
Ensembl_PRO: ENSP00000216121
RefSeq: NP_003625.2, NP_001189431.1
Others
UniRef100: UniRef100_Q9BPW8, UniRef100_B4DQI7
UniRef90: UniRef90_O55125
UniRef50: UniRef50_O75323
UniGene: Hs.173878
CCDS: CCDS13860.1

全选

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