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850768 SIC1

850768

SIC1

cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1

研究结论

Date Results Publications
2015-02-21 10:47:00 Studies propose that Sic1, Cdc37, and Hsp82 may orchestrate parts of the cellular starvation response by regulating transcription factor- and kinase activities. 24909858
2013-02-02 11:59:00 Data indicate that Sic1 function in analogy to its human counterpart p27(Kip1), whose deregulation leads to failure in timing of kinase activation and, therefore, to cancer. 22161326
2012-07-28 10:21:00 Ime2 does not directly catalyze Sic1 phosphorylation to target it for destabilization as Cln1,-2/Cdk1 do during the cell cycle 22393365
2012-07-14 10:36:00 We analyse oscillations of B-type (Clb) cyclins, focusing on the role of their inhibitor Sic1. 21963604
2012-05-12 10:04:00 Individually weak dispersed Sic1 phospho sites engage Cdc4 in a dynamic equilibrium. The multisite nature of this interaction confers cooperative dependence on kinase activity for Sic1 recognition & ubiquitination at equilibrium. 22328159

名称对应

Type IDs
Synonymous BYC1, SDB25
Gene
UniProtKB-ID: SIC1_YEAST
UniprotKB: P38634
UniParc: UPI0000052F58
EMBL: BK006945, U01300, U53880, Z73251, X78309
EnsemblGenome: YLR079W
KO: sce:YLR079W
Nucleutide sequences
EMBL-CDS: AAA20052.1, AAB67583.1, CAA55118.1, DAA09395.1, CAA97638.1
Gene_ORFName: L9449.8
EnsemblGenome_TRS: YLR079W_mRNA
Protein sequencees
EnsemblGenome_PRO: YLR079W
RefSeq: NP_013180.1
Others
UniRef100: UniRef100_P38634
UniRef90: UniRef90_P38634
UniRef50: UniRef50_P38634

全选

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研究热度

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