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850734 STU2

850734

STU2

Stu2p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Stu2p

研究结论

Date Results Publications
2020-02-15 10:04:00 Study identifies a Stu2 mutant that abolishes its kinetochore function and shows that it causes biorientation defects in vivo. Stu2-mediated pathway functions together with the Aurora B-mediated pathway. Altogether, work indicates that cells employ multiple pathways to ensure biorientation and the accuracy of chromosome segregation. 31584935
2019-10-26 11:39:00 Findings raise the possibility that the microtubule polymerization activities mediated by Stu2p are regulated through sumoylation pathways. 29729126
2019-04-20 12:13:00 An unexpected antagonism has been found between the tubulin-binding Stu2 domains (TOGs) and the lattice-binding basic region: lattice binding by the basic region is weak when at least two TOGs engage tubulins, strong when TOGs are empty. 29897335
2017-11-25 15:47:00 TORC1/Kog1 signaling controls Stu2 localization and thereby contributes to proper microtubule cytoskeletal organization in interphase and mitosis. 28972103
2016-12-17 10:46:00 findings reveal an uncharacterized function of Stu2 that is regulated mechanically, such that kinetochore-microtubule attachments are intrinsically stabilized by tension, implicating it in the correction of erroneous kinetochore-microtubule attachments 27156448

名称对应

Type IDs
Gene
UniProtKB-ID: STU2_YEAST
UniprotKB: P46675
UniParc: UPI0000136158
EMBL: X94607, Z73217, U35247, BK006945
EnsemblGenome: YLR045C
KO: sce:YLR045C
Nucleutide sequences
EMBL-CDS: DAA09363.1, AAA79057.1, CAA64292.1, CAA97574.1
Gene_ORFName: L2108
EnsemblGenome_TRS: YLR045C_mRNA
Protein sequencees
EnsemblGenome_PRO: YLR045C
RefSeq: NP_013146.1
Others
UniRef100: UniRef100_P46675
UniRef90: UniRef90_P46675
UniRef50: UniRef50_P46675

全选

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研究热度

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