| Type | Description |
|---|---|
| Definition | mismatch repair protein MLH2 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 11:31:00 | Here the authors show that the budding yeast mismatch repair related MutLbeta complex, Mlh1-Mlh2, specifically interacts with the conserved meiotic Mer3 helicase, which recruits it to recombination hotspots, independently of mismatch recognition. | 28051769 |
| 2014-11-29 10:38:00 | results support a hypothesis that Mlh1-Mlh2 is a non-essential accessory factor that acts to enhance the activity of Mlh1-Pms1 | 24811092 |
| 2010-01-21 00:00:00 | absence of Mlh2p allows some crossovers from the MSH4 pathway to traverse the MUS81-dependent pathway | 15467363 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MLH2_YEAST
UniprotKB:
Q07980
UniParc:
UPI00000531AB
EMBL:
BK006945,
Z73207
EnsemblGenome:
YLR035C
KO:
sce:YLR035C
|
| Nucleutide sequences |
EMBL-CDS:
DAA09353.1,
CAA97559.1
EnsemblGenome_TRS:
YLR035C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR035C
RefSeq:
NP_013135.1
|
| Others |
UniRef100:
UniRef100_Q07980
UniRef90:
UniRef90_Q07980
UniRef50:
UniRef50_Q07980
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33303966 |
Identification of MLH2/hPMS1 dominant mutations that prevent DNA mismatch repair function. Commun Biol Gloria X Reyes , Boyu Zhao , Tobias T Schmidt , Kerstin Gries , Matthias Kloor , Hans Hombauer |
2020-12-10 | - |
| 31351878 |
Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis. Mol Cell Philipp Wild , Aitor Susperregui , Ilaria Piazza , Christian Dörig , Ashwini Oke , Meret Arter , Miyuki Yamaguchi , Alexander T Hilditch , Karla Vuina , Ki Choi Chan , Tatiana Gromova , James E Haber , Jennifer C Fung , Paola Picotti , Joao Matos |
2019-08-22 | - |
| 29158339 |
G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese |
2018-01-04 | - |
| 28428242 |
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28. G3 (Bethesda) Christine Zimmermann , Ignacio Garcia , Manja Omerzu , Pierre Chymkowitch , Beibei Zhang , Jorrit M Enserink |
2017-06-07 | - |
| 28051769 |
Elife Yann Duroc , Rajeev Kumar , Lepakshi Ranjha , Céline Adam , Raphaël Guérois , Khan Md Muntaz , Marie-Claude Marsolier-Kergoat , Florent Dingli , Raphaëlle Laureau , Damarys Loew , Bertrand Llorente , Jean-Baptiste Charbonnier , Petr Cejka , Valérie Borde |
2017-01-04 | - |
| 27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
| 24811092 |
Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. PLoS Genet Christopher S Campbell , Hans Hombauer , Anjana Srivatsan , Nikki Bowen , Kerstin Gries , Arshad Desai , Christopher D Putnam , Richard D Kolodner |
2014-05-01 | - |
| 23390603 |
G3 (Bethesda) Derek M van Pel , Peter C Stirling , Sean W Minaker , Payal Sipahimalani , Philip Hieter |
2013-02-01 | - |
| 23409723 |
Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae. Genome Biol. Mallory A Freeberg , Ting Han , James J Moresco , Andy Kong , Yu-Cheng Yang , Zhi John Lu , John R Yates , John K Kim |
2013-01-01 |
YGR240C-A,
YIR021W-A,
YGR161W-C,
YLR146W-A,
LRE1,
GLK1,
GFD2,
MRPL32,
CIT2,
PGK1,
CTO1,
YCR023C,
PMP1,
RIM1,
PHO87,
IMG1,
CPR4,
PAT1,
TUP1,
RGD2,
YPT1,
TUB2,
RPO41,
RPL22B,
GYP8,
STE2,
GAT1,
HSP12,
YFH7,
CDC14,
QCR6,
SAP155,
YFR045W,
HXK1,
GPI13,
HSP104,
SSA2,
PUF3,
COX17,
COF1,
YBT1,
DNM1,
SNF7,
SED5,
RPL15A,
MLH2,
YLR035C-A,
PDC1,
YLR046C,
RPS0B,
REX2,
RPL22A,
PER33,
MEF1,
RPL10,
XDJ1,
CHA4,
ICT1,
AHP1,
CFT2,
YPS1,
ZRT2,
SLS1,
STM1,
MAS1,
RPS31,
CBF5,
YLR177W,
SAM1,
EMG1,
UPS1,
NOP56,
QRI5,
ENT2,
COA4,
CDC42,
CSC1,
MAP1,
YEF3,
SYM1,
MCP2,
YLR257W,
GSY2,
HSP60,
RPS28B,
DBP9,
YSH1,
YLR278C,
YLR283W,
CTS1,
RPS30A,
GSP1,
EXG1,
ACO1,
IMH1,
RPL38,
RPS25B,
FKS1,
ILV5
|
| 22282571 |
Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res. Sara Sharifpoor , Dewald van Dyk , Michael Costanzo , Anastasia Baryshnikova , Helena Friesen , Alison C Douglas , Ji-Young Youn , Benjamin VanderSluis , Chad L Myers , Balázs Papp , Charles Boone , Brenda J Andrews |
2012-04-01 |
SUS1,
VMA9,
YCL075W,
YCL074W,
VAC17,
MRC1,
PEX34,
KAR4,
PBN1,
LRE1,
SPS22,
MGR1,
YCL042W,
GLK1,
GID7,
ATG22,
SRO9,
STE50,
RRP7,
BIK1,
FUS1,
FRM2,
AGP1,
DCC1,
BUD3,
SGF29,
ILV6,
YCL002C,
RER1,
CDC10,
YCR007C,
SAT4,
RVS161,
ADP1,
YCR016W,
CWH43,
MAK32,
PET18,
SLM5,
RIM1,
SYP1,
BPH1,
SNT1,
ELO2,
PER1,
YCR051W,
THR4,
TAH1,
YCR061W,
BUD31,
RAD18,
SED4,
ATG15,
IMG2,
RSA4,
SOL2,
ERS1,
PAT1,
TRX3,
CSM1,
ABP1,
YCR090C,
KIN82,
YCR102C,
PAU3,
YFL068W,
AGP3,
YFL054C,
ZNF1,
SWP82,
SEC53,
YFL040W,
ACT1,
YPT1,
RPO41,
RIM15,
BST1,
BUD27,
FRS2,
MDJ1,
HSP12,
IES1,
BLM10,
VTC2,
DEG1,
RPN11,
FAR7,
GCN20,
UBP6,
DCV1,
CMK1,
GSY1,
PES4,
PTR3,
MET10,
RRT5,
RPL29,
RSC8,
SAP155
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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