| Type | Description |
|---|---|
| Definition | DNA helicase RAD5 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:19:00 | MutSalpha deficiency increases tolerance to DNA damage in yeast lacking postreplication repair. | 32470850 |
| 2019-12-14 10:51:00 | The direct effect of Rad5 on replication forks in vivo, increased recombination, and cisplatin sensitivity predicts similar consequences for dysregulated HLTF in cancer. | 31350889 |
| 2019-06-29 11:19:00 | Rad5 binds to the sites of stressed DNA replication forks, where it recruits TLS polymerase, DNA polymerase zeta, to repair single-stranded DNA (ssDNA) gaps, preventing mitotic defects and chromosome breaks. | 30733119 |
| 2019-03-09 12:39:00 | Cdc28/CDK1 modulates Rad5 stability by phosphorylation during the cell cycle, suggesting a crosstalk between the phosphorylation and degradation of Rad5. | 30256854 |
| 2018-10-20 11:20:00 | By analyzing the formation of Rad5 foci after MMS treatment, we showed that some specific DNA structures rather than mono-ubiquitination of proliferating cell nuclear antigen are required for the recruitment of Rad5 to the damaged site | 29396601 |
| Type | IDs |
|---|---|
| Synonymous | REV2, SNM2 |
| Gene |
UniProtKB-ID:
RAD5_YEAST
UniprotKB:
P32849
UniParc:
UPI000013307E
EMBL:
Z73204,
M96644,
S46103,
BK006945
EnsemblGenome:
YLR032W
KO:
sce:YLR032W
|
| Nucleutide sequences |
EMBL-CDS:
CAA97556.1,
AAA34951.1,
AAB23590.1,
DAA09350.1
EnsemblGenome_TRS:
YLR032W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR032W
RefSeq:
NP_013132.1
|
| Others |
UniRef100:
UniRef100_P32849
UniRef90:
UniRef90_P32849
UniRef50:
UniRef50_P32849
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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