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850712 SNF7

850712

SNF7

ESCRT-III subunit protein SNF7

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ESCRT-III subunit protein SNF7

研究结论

Date Results Publications
2017-12-02 10:58:00 The major ESCRT-III subunit Snf7 localizes transiently to vesicles and tubules surrounded by a cup-shaped membrane and this was accelerated in vps4Delta cells, correlating with increased Acb1 secretion. 27115345
2017-05-20 14:34:00 Novel mutations has been characterized in ESCRT-III Snf7 that trigger activation, and a novel role have been assigned to Bro1, the yeast ALIX ortholog, in Snf7 assembly. 27074665
2016-10-08 11:50:00 Using a combination of biochemical and genetic approaches, both in vitro and in vivo, we demonstrate that mutations on these protein interfaces halt Snf7 assembly and block endosomal sorting complexes required for transport function. 26670543
2014-06-28 12:46:00 Snf7 alpha6 helix is crucial for binding of Bro1 and Rim20 in vivo and is indispensable for the multivesicular body sorting. 24058170
2014-05-31 11:25:00 Binding of Vps4 to ESCRT-III, coordinated by interactions with Vps2 and Snf7, is coupled to membrane neck constriction during intraluminal vesicle formation. 24711499

名称对应

Type IDs
Synonymous DID1, RNS4, VPL5, VPS32
Gene
UniProtKB-ID: SNF7_YEAST
UniprotKB: P39929
UniParc: UPI0000135B2D
EMBL: Z73197, L09751, BK006945, AY558202
EnsemblGenome: YLR025W
KO: sce:YLR025W
Nucleutide sequences
EMBL-CDS: AAS56528.1, CAA97548.1, DAA09343.1
EnsemblGenome_TRS: YLR025W_mRNA
Protein sequencees
EnsemblGenome_PRO: YLR025W
RefSeq: NP_013125.1
Others
UniRef100: UniRef100_P39929
UniRef90: UniRef90_P39929
UniRef50: UniRef50_P39929

全选

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研究热度

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