Type | Description |
---|---|
Definition | flavin-dependent quinone reductase |
Date | Results | Publications |
---|---|---|
2015-04-04 10:45:00 | Using hexahistidine tagged, recombinant Lot6p, the authors determined the steady-state enzyme kinetic parameters with both NADH and NADPH as electron donors; no cooperativity was observed with these substrates. | 24866129 |
2010-01-21 00:00:00 | LOT6 is a FMN-dependent reductase with a potential role in quinone detoxification. | 17298444 |
2010-01-21 00:00:00 | The authors propose that Lot6p is directly involved in the control of the apoptosis-like cell death in yeast. | 19709309 |
2010-01-21 00:00:00 | Hydride transfer, and not an enzyme conformational change, is rate-determining in the Lot6 reductive half-reaction. In the oxidative half-reaction, reduced enzyme reacted in a single phase with six quinone substrates tested. | 19618916 |
2010-01-21 00:00:00 | Lot6-proteasome complex can be regarded as a redox switch in which the quinone reductase acts as a sensor for oxidative stress | 19029946 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
LOT6_YEAST
UniprotKB:
Q07923
UniParc:
UPI0000069F5C
EMBL:
AY558199,
Z73183,
BK006945
EnsemblGenome:
YLR011W
KO:
sce:YLR011W
|
Nucleutide sequences |
EMBL-CDS:
AAS56525.1,
DAA09329.1,
CAA97533.1
EnsemblGenome_TRS:
YLR011W_mRNA
|
Protein sequencees |
EnsemblGenome_PRO:
YLR011W
RefSeq:
NP_013111.1
|
Others |
UniRef100:
UniRef100_Q07923
UniRef90:
UniRef90_Q07923
UniRef50:
UniRef50_Q07923
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
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