| Type | Description |
|---|---|
| Definition | cofilin |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:08:00 | Cyclase-associated protein (CAP) and Cofilin synergize to processively depolymerize actin filament pointed ends at a rate 330-fold faster than spontaneous depolymerization. Single molecule imaging further reveals that hexameric CAP molecules interact with the pointed ends of Cofilin-decorated filaments for several seconds at a time, removing approximately 100 actin subunits per binding event. | 31757952 |
| 2017-08-05 12:37:00 | Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics. | 27153537 |
| 2015-12-26 12:19:00 | Using multi-color total internal reflection fluorescence microscopy, the study shows that Crn1 enhances Cof1-mediated severing by accelerating Cof1 binding to actin filament sides. | 26299936 |
| 2013-06-08 13:03:00 | Data indicate that the combined activities of cofilin and Srv2/CAP lead to enhanced filament severing and support an emerging view that actin disassembly is controlled not by cofilin alone, but by a more complex set of factors working in concert. | 23135996 |
| 2012-10-13 10:25:00 | Findings highlight the conserved role of cofilin and SPCA1/Pmr1 in sorting of the soluble secretory proteins at the trans-Golgi network/late Golgi membranes in eukaryotes. | 22553351 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
COFI_YEAST
UniprotKB:
Q03048
UniParc:
UPI0000110C55
EMBL:
Z47973,
D13230,
Z73155,
BK006945,
Z14971,
S52662
EnsemblGenome:
YLL050C
KO:
sce:YLL050C
|
| Nucleutide sequences |
EMBL-CDS:
AAA13256.1,
DAA09274.1,
CAA97502.1,
CAA88007.1,
BAA02514.1,
CAA78694.1
Gene_ORFName:
L0596
EnsemblGenome_TRS:
YLL050C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLL050C
RefSeq:
NP_013050.1
|
| Others |
UniRef100:
UniRef100_Q03048
UniRef90:
UniRef90_Q03048
UniRef50:
UniRef50_Q03048
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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