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850636 SSA2

850636

SSA2

Hsp70 family chaperone SSA2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Hsp70 family chaperone SSA2

研究结论

Date Results Publications
2020-09-19 16:30:00 The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate. 31825716
2019-10-26 11:37:00 Hsp110 (Sse1 and Sse2) associates with the 19S regulatory particle of the 26S proteasome and interacts with Hsp70 (Ssa1, Ssa2) to facilitate the delivery of Hsp70 substrates for proteasomal degradation. 29507114
2019-10-05 12:03:00 Yeast ACO1 mitochondrial import is modulated by interactions of its C and N terminal domains and SSA1/SSA2. 29651044
2019-08-10 12:34:00 The authors mapped a discrete Hsp70 binding site on Hsf1 to a C-terminal segment known as conserved element 2 (CE2). In vitro, CE2 binds to Hsp70 with low affinity (9 microM), in agreement with model requirements. In cells, removal of CE2 resulted in increased basal Hsf1 activity and delayed deactivation during heat shock, while tandem repeats of CE2 sped up Hsf1 deactivation. 29393852
2017-06-10 10:12:00 Molecular chaperones of the Hsp70 family, SSA1 and SSA2, assist in the assembly of 20S proteasomes. 28322792

名称对应

Type IDs
Synonymous YG102
Gene
UniProtKB-ID: HSP72_YEAST
UniprotKB: P10592
UniParc: UPI000016838F
EMBL: Z73129, X12927, BK006945, X97560
EnsemblGenome: YLL024C
KO: sce:YLL024C
Nucleutide sequences
EMBL-CDS: CAA66167.1, DAA09296.1, CAA31394.1, CAA97472.1
Gene_ORFName: L0931
EnsemblGenome_TRS: YLL024C_mRNA
Protein sequencees
EnsemblGenome_PRO: YLL024C
RefSeq: NP_013076.1
Others
UniRef100: UniRef100_P10592
UniRef90: UniRef90_P10591
UniRef50: UniRef50_P10591

全选

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研究热度

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