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850551 LOC1

850551

LOC1

Loc1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Loc1p

研究结论

Date Results Publications
2020-04-25 11:24:00 Results found that Puf6 and Loc1 are critical to maintaining the stability of Rpl43. Mutation of any one protein results in blockages at similar steps during biogenesis. The C-terminus of Loc1 is more important for interaction with Puf6 and Rpl43. Correct formation of the Puf6, Loc1, and Rpl43 ternary complex is required to properly proceed to the next step in 60S biogenesis. 31779129
2018-07-21 11:27:00 Transcriptomic analyses revealed small changes in the level of Ty1 transcripts or efficiency of translation initiation in a loc1Delta mutant. Importantly, a loc1Delta mutant had defects in assembly of Gag complexes and packaging Ty1 RNA. 29046400
2017-05-20 12:02:00 Puf6 and Loc1 facilitate Rpl43 loading and are sequentially released from 60S after incorporation of Rpl43 into ribosomes in yeast. 27458021
2010-01-21 00:00:00 She2p interacts with both Loc1p and Puf6p and excluding She2p from the nucleus decreases this interaction. 19244342
2010-01-21 00:00:00 has a role in rRNA processing and nuclear export of 60S subunits 16871394

名称对应

Type IDs
Gene
UniProtKB-ID: LOC1_YEAST
UniprotKB: P43586
UniParc: UPI0000053227
EMBL: D50617, AY557809, BK006940
EnsemblGenome: YFR001W
KO: sce:YFR001W
Nucleutide sequences
EMBL-CDS: AAS56135.1, DAA12441.1, BAA09240.1
EnsemblGenome_TRS: YFR001W_mRNA
Protein sequencees
EnsemblGenome_PRO: YFR001W
RefSeq: NP_116656.1
Others
UniRef100: UniRef100_A7A239
UniRef90: UniRef90_A7A239
UniRef50: UniRef50_A3GHA4

全选

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研究热度

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