| Type | Description |
|---|---|
| Definition | cohesin subunit SMC1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:00:00 | ATP-binding and Smc1-Smc3 heterodimerization promote conformational changes within the ATPase that are transmitted to the Smc coiled-coil domains. | 32066964 |
| 2020-02-15 13:26:00 | This study confirmed the interaction between cohesin (containing SMC1) and FACT complex (containing Spt16) in metaphase arrests using cells that expressed SMC1-6HA and SPT16-9MYC to validate that cohesin physically interacts with this histone chaperone. | 31582854 |
| 2017-09-09 11:31:00 | A reversible association between Smc1 and Smc3 coiled coils is regulated by lysine acetylation and is required for cohesin association with the DNA. | 27618487 |
| 2017-06-24 11:24:00 | We identified a large number of mutations in the CC region of both Smc1 and Smc3... we introduced them to the yeast Smc1 and Smc3 CC domains and characterized the effect of these mutant alleles on cohesin's function. We identified a missense mutation in the region of the kink domain of Smc3, which was previously identified in kidney carcinoma | 27307603 |
| 2016-10-08 12:08:00 | These results also suggest that Eco1 promotes cohesion by modulating the ATPase cycle of DNA-bound cohesin in a state that is permissive for DNA tethering and refractory to Wpl1 inhibition. | 26583750 |
| Type | IDs |
|---|---|
| Synonymous | CHL10 |
| Gene |
UniProtKB-ID:
SMC1_YEAST
UniprotKB:
P32908
UniParc:
UPI00000530B0
EMBL:
L00602,
BK006940,
D50617
EnsemblGenome:
YFL008W
KO:
sce:YFL008W
|
| Nucleutide sequences |
EMBL-CDS:
BAA09230.1,
AAA16595.1,
DAA12432.1
EnsemblGenome_TRS:
YFL008W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YFL008W
RefSeq:
NP_116647.1
|
| Others |
UniRef100:
UniRef100_P32908
UniRef90:
UniRef90_P32908
UniRef50:
UniRef50_P32908
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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