Type | Description |
---|---|
Definition | transcription factor HAC1 |
Date | Results | Publications |
---|---|---|
2021-03-29 10:55:00 | The consensus RNA structure of the Hac1 mRNA defines the unconventional splice sites and it is well conserved in Fungi and Metazoa | 21593604 |
2020-12-12 13:23:00 | Expression and function of an Hac1-regulated multi-copy xylanase gene in Saccharomyces cerevisiae. | 32669586 |
2020-04-04 12:07:00 | The authors show that phosphorylation of two different HAC1 splicing intermediates is required for their degradation by the 5'-->3' exonuclease Xrn1 to enact opposing effects on the UPR. We also found that ligated but 2'-phosphorylated HAC1 mRNA is cleaved, yielding a decay intermediate with both 5'- and 2'-phosphates at its 5'-end that inhibit 5'-->3' decay and suggesting that Ire1 degrades incompletely processed HAC1. | 30874502 |
2019-07-06 11:18:00 | Endoplasmic reticulum stress causes a diminished mRNA decay, thus resulting in the production of a population with an increased abundance of pre-HAC1 mRNA carrying an intact bipartite element, which facilitates its more efficient recruitment to Ire1p foci. | 29165698 |
2017-10-21 11:14:00 | Here, the authors show that a combination of inhibited translation initiation and accelerated protein degradation-both dependent on the intron-prevents the accumulation of Hac1 protein when the unfolded protein response is inactive. | 27692069 |
Type | IDs |
---|---|
Synonymous | ERN4, IRE15 |
Gene |
UniProtKB-ID:
HAC1_YEAST
UniprotKB:
P41546
UniParc:
UPI0000157F61,
UPI0000157F60
EMBL:
BK006940,
D26506,
D50617,
D86413
EnsemblGenome:
YFL031W
KO:
sce:YFL031W
|
Nucleutide sequences |
EMBL-CDS:
BAA05513.1,
DAA12409.1,
BAA24425.1,
BAA19565.1
EnsemblGenome_TRS:
YFL031W_mRNA
|
Protein sequencees |
EnsemblGenome_PRO:
YFL031W
RefSeq:
NP_116622.1
|
Others |
UniRef100:
UniRef100_P41546
UniRef90:
UniRef90_P41546
UniRef50:
UniRef50_P41546
|
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