| Type | Description |
|---|---|
| Definition | poly(ADP-ribose) glycohydrolase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-04 12:50:00 | PARG overexpression partially but significantly inhibited ASK3 dephosphorylation under hyperosmotic stress, while the glycohydrolase-inactive PARG mutant did not. | 33649309 |
| 2021-02-13 13:23:00 | Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. | 33046907 |
| 2021-01-23 12:59:00 | PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains. | 32439163 |
| 2020-07-25 11:13:00 | DNA methylation-mediated repression of exosomal miR-652-5p expression promotes oesophageal squamous cell carcinoma aggressiveness by targeting PARG and VEGF pathways | 32343702 |
| 2020-07-04 10:54:00 | PARG, an enzyme family that hydrolyzes poly(ADP-ribose), is sufficient to dissociate damaged DNA-rich compartments in vitro and initiates the nucleocytoplasmic shuttling of FUS in cells. | 31067465 |
| Type | IDs |
|---|---|
| Synonymous | PARG99 |
| Gene |
UniProtKB-ID:
PARG_HUMAN
UniprotKB:
Q86W56
UniParc:
UPI000018CEA9,
UPI00003BECAE,
UPI00003BECAD,
UPI00029CD9A8,
UPI000156572D
EMBL:
EF382674,
AY575848,
AK302560,
AK314909,
AF005043,
BC050560,
AY575849,
AK295786,
AY258587,
BC052966,
JQ890226
Ensembl:
ENSG00000227345
KO:
hsa:8505
|
| Nucleutide sequences |
EMBL-CDS:
AAT66421.1,
AAH50560.1,
AAP83314.1,
ABR10027.1,
AAH52966.1,
AAB61614.1,
BAG63826.1,
AAT66422.1,
BAG37421.1,
BAG58607.1,
AFM56043.1
Ensembl_TRS:
ENST00000616448,
ENST00000402038
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384408,
ENSP00000484285
RefSeq:
XP_011538610.1,
NP_001290418.1,
NP_003622.2,
NP_001311310.1,
NP_001290416.1,
NP_001290415.1,
XP_011538607.1
|
| Others |
UniRef100:
UniRef100_Q86W56
UniRef90:
UniRef90_Q86W56
UniRef50:
UniRef50_Q86W56
UniGene:
Hs.535298,
Hs.732225
CCDS:
CCDS73130.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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