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850456 CDC50

850456

CDC50

aminophospholipid translocase regulatory protein CDC50

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition aminophospholipid translocase regulatory protein CDC50

研究结论

Date Results Publications
2019-10-12 12:26:00 cryo-electron microscopy structure of the P4-ATPase Drs2p-Cdc50p; three structures are presented that represent the complex in an autoinhibited, an intermediate and a fully activated state 31243363
2018-03-26 10:37:00 Cdc50p, a membrane protein in the endosomal/trans-Golgi network compartments, is a noncatalytic subunit of Drs2p, which is implicated in translocation of phospholipids across lipid bilayers. (cdc50p) 16195350
2017-07-15 12:02:00 activation of the Drs2p-Cdc50p flippase follows a multistep mechanism, with preliminary release of a number of constraints, possibly through the binding of regulatory proteins in the trans-Golgi network, followed by full activation by PI4P 28302728
2016-09-24 12:08:00 we describe the overexpression of a yeast lipid flippase complex, namely the P4-ATPase Drs2p and its associated subunit Cdc50p, in a coordinated manner. 26695021
2012-06-23 12:12:00 Phosphatidylinositol-4-phosphate tightly controls Drs2p-catalyzed lipid transport and establish the functional relevance of the Drs2p.Cdc50p complex. 22351780

名称对应

Type IDs
Gene
UniProtKB-ID: CDC50_YEAST
UniprotKB: P25656
UniParc: UPI000013A7A0
EMBL: BK006937, X59720
EnsemblGenome: YCR094W
KO: sce:YCR094W
Nucleutide sequences
EMBL-CDS: CAA42249.1, DAA07563.1
Gene_ORFName: YCR94W
EnsemblGenome_TRS: YCR094W_mRNA
Protein sequencees
EnsemblGenome_PRO: YCR094W
RefSeq: NP_010018.1
Others
UniRef100: UniRef100_P25656
UniRef90: UniRef90_P25656
UniRef50: UniRef50_P25656

全选

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研究热度

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