| Type | Description |
|---|---|
| Definition | aminophospholipid translocase regulatory protein CDC50 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 12:26:00 | cryo-electron microscopy structure of the P4-ATPase Drs2p-Cdc50p; three structures are presented that represent the complex in an autoinhibited, an intermediate and a fully activated state | 31243363 |
| 2018-03-26 10:37:00 | Cdc50p, a membrane protein in the endosomal/trans-Golgi network compartments, is a noncatalytic subunit of Drs2p, which is implicated in translocation of phospholipids across lipid bilayers. (cdc50p) | 16195350 |
| 2017-07-15 12:02:00 | activation of the Drs2p-Cdc50p flippase follows a multistep mechanism, with preliminary release of a number of constraints, possibly through the binding of regulatory proteins in the trans-Golgi network, followed by full activation by PI4P | 28302728 |
| 2016-09-24 12:08:00 | we describe the overexpression of a yeast lipid flippase complex, namely the P4-ATPase Drs2p and its associated subunit Cdc50p, in a coordinated manner. | 26695021 |
| 2012-06-23 12:12:00 | Phosphatidylinositol-4-phosphate tightly controls Drs2p-catalyzed lipid transport and establish the functional relevance of the Drs2p.Cdc50p complex. | 22351780 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CDC50_YEAST
UniprotKB:
P25656
UniParc:
UPI000013A7A0
EMBL:
BK006937,
X59720
EnsemblGenome:
YCR094W
KO:
sce:YCR094W
|
| Nucleutide sequences |
EMBL-CDS:
CAA42249.1,
DAA07563.1
Gene_ORFName:
YCR94W
EnsemblGenome_TRS:
YCR094W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YCR094W
RefSeq:
NP_010018.1
|
| Others |
UniRef100:
UniRef100_P25656
UniRef90:
UniRef90_P25656
UniRef50:
UniRef50_P25656
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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