| Type | Description |
|---|---|
| Definition | Csm1p |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:20:00 | Csm1 binds two conserved motifs in Dsn1, one (termed Box 1) representing the ancestral, widely conserved monopolin binding motif and a second (termed Box 2-3) with a likely role in enforcing specificity of sister kinetochore crosslinking. We find that Box 1 and Box 2-3 bind the same conserved hydrophobic cavity on Csm1, suggesting competition or handoff between these motifs. More information in the paper. | 31037469 |
| 2019-02-09 11:25:00 | Binding to Csm1 regulates substrate specificity of the Ulp2 protease. | 29903909 |
| 2014-01-11 12:14:00 | we demonstrate that interaction of monopolin subunit Csm1 with the N-terminal domain of MIND complex subunit Dsn1, is essential for both the association of monopolin with kinetochores and for monopolar attachment of sister kinetochores during meiosis | 23861669 |
| 2011-01-29 10:09:00 | The Lrs4-Csm1 complex localize to kinetochores during anaphase and is important for ensuring accurate chromosome segregation. (Csm1 protein) | 20818155 |
| 2010-09-20 11:27:00 | Csm1/Lrs4 (Psc1/Mde4) functions as a molecular clamp, crosslinking kinetochore components to enforce sister chromatid co-orientation in S. cerevisiae meiosis I and to suppress merotelic attachment in S. pombe mitosis. | 20723757 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CSM1_YEAST
UniprotKB:
P25651
UniParc:
UPI000013A767
EMBL:
X59720,
AY558153,
BK006937
EnsemblGenome:
YCR086W
KO:
sce:YCR086W
|
| Nucleutide sequences |
EMBL-CDS:
AAS56479.1,
DAA07555.1,
CAA42261.1
Gene_ORFName:
YCR86W
EnsemblGenome_TRS:
YCR086W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YCR086W
RefSeq:
NP_010009.1
|
| Others |
UniRef100:
UniRef100_P25651
UniRef90:
UniRef90_P25651
UniRef50:
UniRef50_P25651
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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