| Type | Description |
|---|---|
| Definition | autophagy related 4D cysteine peptidase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:16:00 | Human HAP1 and HeLa cells lacking ATG4B exhibit a severe but incomplete defect in LC3/GABARAP processing and autophagy. By further genetic depletion of ATG4 isoforms using CRISPR-Cas9 and siRNA we uncover that ATG4A, ATG4C and ATGD all contribute to residual priming activity, which is sufficient to enable lipidation of endogenous GABARAPL1 on autophagic structures. | 30661429 |
| 2019-01-19 11:27:00 | High ATG4D expression is associated with Colorectal Cancer. | 30374741 |
| 2017-10-28 11:12:00 | study elucidated a novel Malat1-miR-101-STMN1/RAB5A/ATG4D regulatory network that Malat1 activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma cells | 28834690 |
| 2017-02-04 11:21:00 | This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D, ATG9A and ATG9B promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas. | 27265029 |
| 2014-01-11 10:40:00 | The actions of ATG4 family members (particularly ATG4B) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts. | 23508006 |
| Type | IDs |
|---|---|
| Synonymous | APG4-D, APG4D, AUTL4 |
| Gene |
UniProtKB-ID:
ATG4D_HUMAN,
B4DGM8_HUMAN
UniprotKB:
Q86TL0,
B4DGM8
UniParc:
UPI00017A6DB3,
UPI000000DCA0,
UPI00000707A8
EMBL:
BC007639,
AK294676,
AJ312332,
AC011461,
BC016845,
BC068992,
CH471106
Ensembl:
ENSG00000130734
KO:
hsa:84971
|
| Nucleutide sequences |
EMBL-CDS:
AAH07639.1,
EAW84116.1,
AAH16845.1,
CAC85951.1,
AAH68992.1,
BAG57839.1
Ensembl_TRS:
ENST00000309469
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311318
RefSeq:
NP_116274.3,
XP_006722990.1,
NP_001268433.1
|
| Others |
UniRef100:
UniRef100_B4DGM8,
UniRef100_Q86TL0
UniRef90:
UniRef90_A0A0D9R439,
UniRef90_Q86TL0
UniRef50:
UniRef50_Q86TL0,
UniRef50_R4GER2
UniGene:
Hs.512799
CCDS:
CCDS12241.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员