| Type | Description |
|---|---|
| Definition | PTPRF interacting protein alpha 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 10:13:00 | Hypoxia appears to up-regulate the expression of liprin-alpha4, which induces the expression of HIF1alpha. HIF1alpha contributes to increased proliferation and lower chemosensitivity. Therefore, inhibition of liprin-alpha4 or HIF1alpha led to reduced proliferation and increased chemosensitivity of SBC-5 cells. | 30842147 |
| 2018-06-02 11:45:00 | The results identify PP1IFA4 loci associated with early onset atrial fibrillation in a Korean population. | 28460022 |
| 2017-12-16 12:31:00 | Data show that liprin-alpha4 plays a pivotal role in inducing malignant phenotypes such as increased proliferation and invasion in pancreatic cancer, and that liprin-alpha4 could be a new effective therapeutic target for pancreatic cancer. | 29187440 |
| 2011-12-31 11:26:00 | presence of Liprin-alpha4 and nickel increased tyrosine phosphatase activity that reduced the global levels of tyrosine phosphorylation in the cell | 21829649 |
| 2010-11-13 11:04:00 | liprin-alpha4 is a hypoxia-induced gene potentially involved in cell-cell adhesion | 20599943 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LIPA4_HUMAN,
B3KN22_HUMAN,
B4DIS5_HUMAN
UniprotKB:
O75335,
B3KN22,
B4DIS5
UniParc:
UPI000023B84C,
UPI000015F522,
UPI00017A721F,
UPI00001C0CC6,
UPI0001661778
EMBL:
AK126624,
AL451082,
BC132923,
EF428334,
AC096632,
BC144262,
BC132925,
AF034801,
AC105940,
AK023365,
AB020704,
AK295757
Ensembl:
ENSG00000143847
KO:
hsa:8497
|
| Nucleutide sequences |
EMBL-CDS:
AAI32924.1,
ABR09268.1,
BAA74920.1,
AAC26102.1,
AAI32926.1,
AAI44263.1,
BAC86617.1,
BAG51184.1,
BAG58587.1
Ensembl_TRS:
ENST00000272198,
ENST00000295706,
ENST00000447715,
ENST00000599966
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402576,
ENSP00000272198,
ENSP00000295706,
ENSP00000471264
RefSeq:
NP_001291261.1,
XP_011508372.1,
XP_016858096.1,
XP_016858099.1,
XP_006711649.1,
XP_016858098.1,
NP_001291260.1,
XP_016858095.1
|
| Others |
UniRef100:
UniRef100_O75335,
UniRef100_B4DIS5,
UniRef100_B3KN22
UniRef90:
UniRef90_B4DIS5,
UniRef90_O75335,
UniRef90_B3KN22
UniRef50:
UniRef50_O75335,
UniRef50_M3W2T4,
UniRef50_A0A060Z532
UniGene:
Hs.153648
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员