| Type | Description |
|---|---|
| Definition | TOX high mobility group box family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 11:19:00 | A haplotype block across a 24-kb region within the TOX2 gene reached genome-wide significance in haplotype-block-based regional heritability mapping. Single-SNP- and haplotype-based association tests demonstrated that five of nine genotyped SNPs and two haplotypes within this block were significantly associated with major depressive disorder. | 28153336 |
| 2015-02-28 13:08:00 | TOX2 plays a crucial role in controlling normal NK cell development by acting upstream of TBX21 transcriptional regulation | 25352127 |
| 2012-08-25 10:20:00 | A novel aberrantly hypermethylated CpG island in cancer was discovered within the TOX2 promoter. TOX2 was unmethylated in normal cells. Expression of two novel TOX2 transcripts was significantly reduced in primary lung tumors. | 22496870 |
| 2010-06-30 22:04:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2009-04-01 21:32:00 | Observational study of gene-disease association. (HuGE Navigator) | 19240061 |
| Type | IDs |
|---|---|
| Synonymous | C20orf100, GCX-1, GCX1, dJ1108D11.2, dJ495O3.1 |
| Gene |
UniProtKB-ID:
TOX2_HUMAN
UniprotKB:
Q96NM4
UniParc:
UPI000016069C,
UPI000040F535,
UPI00001285F3,
UPI000002A753
EMBL:
AK055135,
AK289906,
AL121587,
AL034419,
AL353797,
AL035089,
BC007636,
CH471077
Ensembl:
ENSG00000124191
KO:
hsa:84969
|
| Nucleutide sequences |
EMBL-CDS:
BAF82595.1,
EAW75944.1,
EAW75945.1,
EAW75946.1,
BAB70860.1
Ensembl_TRS:
ENST00000358131,
ENST00000341197,
ENST00000372999,
ENST00000423191
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362090,
ENSP00000344724,
ENSP00000390278,
ENSP00000350849
RefSeq:
NP_001092267.1,
NP_001092266.1,
NP_116272.1,
XP_016883598.1,
NP_001092268.1,
XP_006723947.1
|
| Others |
UniRef100:
UniRef100_Q96NM4
UniRef90:
UniRef90_Q96NM4
UniRef50:
UniRef50_Q96NM4
UniGene:
Hs.26608
CCDS:
CCDS42875.1,
CCDS13324.1,
CCDS46603.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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