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84959 UBASH3B

84959

UBASH3B

ubiquitin associated and SH3 domain containing B

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquitin associated and SH3 domain containing B

研究结论

Date Results Publications
2021-01-09 13:28:00 An unexpected 2-histidine phosphoesterase activity of suppressor of T-cell receptor signaling protein 1 contributes to the suppression of cell signaling. 32371395
2020-07-04 12:49:00 These studies help define a critical role of Ubash3b in leukemia 31399640
2020-04-18 10:43:00 the UBASH3B gene rs4936742 (T > C) polymorphism is associated with an increased risk of Behcet's disease, especially non-ocular BD, in Iranian population. We could not find any susceptibility role of this genetic locus for posterior uveitis in Behcet's disease. 30289285
2020-02-08 10:18:00 Sts-1 is a negative regulator. 30962580
2019-10-05 10:57:00 UBASH3A/STS-2/TULA exhibits substantial homology to UBASH3B/STS-1/TULA-2, but possesses only a small fraction of phosphatase activity of UBASH3B/STS-1/TULA-2, and thus, its regulatory effect may be based also on the phosphatase-independent mechanisms. Critical physiologic effects of these proteins have been demonstrated in T lymphocytes, platelets, stem cells, and other important cell types. 30076707

名称对应

Type IDs
Synonymous STS-1, STS1, TULA-2, TULA2, p70
Gene
UniProtKB-ID: UBS3B_HUMAN
UniprotKB: Q8TF42
UniParc: UPI0000047471
EMBL: AK222846, AF425252, AK075203, AB075839, BC007541, AK222843
Ensembl: ENSG00000154127
KO: hsa:84959
Nucleutide sequences
EMBL-CDS: BAC11468.1, BAD96563.1, BAD96566.1, AAH07541.2, BAB85545.1, AAL16953.1
Ensembl_TRS: ENST00000284273
Protein sequencees
Ensembl_PRO: ENSP00000284273
RefSeq: XP_011541343.1, NP_116262.2, XP_005271769.1, NP_001350294.1
Others
UniRef100: UniRef100_Q8TF42
UniRef90: UniRef90_Q8TF42
UniRef50: UniRef50_Q8TF42
UniGene: Hs.444075
CCDS: CCDS31694.1

全选

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