| Type | Description |
|---|---|
| Definition | tensin 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Histone acetyltransferase p300 mediates the upregulation of CTEN induced by the activation of EGFR signaling in cancer cells. | 33310188 |
| 2021-04-03 13:35:00 | Tensin4 promotes invasion and migration of gastric cancer cells via regulating AKT/GSK-3beta/snail signaling pathway. | 32534709 |
| 2020-05-16 11:14:00 | The authors propose that TNS4 plays a crucial role in CRC tumorigenesis, and that suppression of TNS4 would be an effective therapeutic strategy in treating a subset of cetuximab-refractory CRC patients including KRAS activating mutations. | 31409052 |
| 2020-04-11 12:32:00 | analysis of cten force-induced recruitment along keratin network in epithelial cells | 31527270 |
| 2020-02-22 11:09:00 | Src is a novel and functionally important target of the Cten signaling pathway and that Cten protein causes post-transcriptional stabilization of Src in promoting EMT and possibly metastasis in colorectal cancer | 31290243 |
| Type | IDs |
|---|---|
| Synonymous | CTEN, PP14434 |
| Gene |
UniProtKB-ID:
TENS4_HUMAN,
Q6PJP3_HUMAN
UniprotKB:
Q8IZW8,
Q6PJP3
UniParc:
UPI000013CE0F,
UPI00001BD9F8
EMBL:
AC018629,
AF370421,
AF417488,
AK027856,
BC013373,
BC018706
Ensembl:
ENSG00000131746
KO:
hsa:84951
|
| Nucleutide sequences |
EMBL-CDS:
AAN32666.1,
BAB55413.1,
AAH18706.1,
AAQ15257.1,
AAH13373.1
Gene_ORFName:
PP14434
Ensembl_TRS:
ENST00000254051
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000254051
RefSeq:
XP_016880725.1,
XP_016880726.1,
NP_116254.4,
XP_005257801.1
|
| Others |
UniRef100:
UniRef100_Q6PJP3,
UniRef100_Q8IZW8
UniRef90:
UniRef90_H2NU75,
UniRef90_Q8IZW8
UniRef50:
UniRef50_H2NU75,
UniRef50_Q8IZW8
UniGene:
Hs.438292
CCDS:
CCDS11368.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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