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8495 PPFIBP2

8495

PPFIBP2

PPFIA binding protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition PPFIA binding protein 2

研究结论

Date Results Publications
2019-06-01 12:37:00 germline mutations in a novel gene, PPFIBP2, differentiated risk for lethal prostate cancer from low-risk cases and were associated with shorter survival times after diagnosis. 30043417
2016-12-17 12:05:00 Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. 26663347
2016-05-07 12:17:00 rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. 26443449
2013-02-16 11:04:00 Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. 22328529
2011-07-16 11:30:00 analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 21462929

名称对应

Type IDs
Synonymous Cclp1
Gene
UniProtKB-ID: LIPB2_HUMAN
UniprotKB: Q8ND30
UniParc: UPI00001C1EF8, UPI0000DFF743, UPI0001F7886B
EMBL: AL834426, BC021714, AC104237, AK296718, AC107884, AF034803
Ensembl: ENSG00000166387
KO: hsa:8495
Nucleutide sequences
EMBL-CDS: CAD39087.2, AAC26104.1, AAH21714.1, BAH12419.1
Ensembl_TRS: ENST00000299492, ENST00000528883, ENST00000530181
Protein sequencees
Ensembl_PRO: ENSP00000435469, ENSP00000299492, ENSP00000437321
RefSeq: XP_006718416.1, XP_016873936.1, NP_001338782.2, NP_001338784.2, XP_024304493.1, NP_003612.3, XP_011518717.1, NP_001338786.2, NP_001338787.2, NP_001243497.2, NP_001338789.2, XP_011518719.1, XP_011518716.1, XP_006718412.1, NP_001243498.2, NP_001338788.2, XP_005253234.1, XP_011518722.1, NP_001338791.2, XP_011518715.1, NP_001338783.2, NP_001338785.2, XP_011518720.1, NP_001338790.2, XP_006718415.1, XP_011518718.1
Others
UniRef100: UniRef100_Q8ND30
UniRef90: UniRef90_Q8ND30
UniRef50: UniRef50_Q8ND30
UniGene: Hs.655714, Hs.740974
CCDS: CCDS58117.1, CCDS58116.1, CCDS31419.1

全选

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