| Type | Description |
|---|---|
| Definition | autophagy related 4C cysteine peptidase |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:18:00 | CAV1 and ATG4C serve as useful prognostic biomarkers and candidate therapeutic targets in EOC | 32401768 |
| 2020-06-20 10:16:00 | Human HAP1 and HeLa cells lacking ATG4B exhibit a severe but incomplete defect in LC3/GABARAP processing and autophagy. By further genetic depletion of ATG4 isoforms using CRISPR-Cas9 and siRNA we uncover that ATG4A, ATG4C and ATGD all contribute to residual priming activity, which is sufficient to enable lipidation of endogenous GABARAPL1 on autophagic structures. | 30661429 |
| 2019-12-21 12:01:00 | our results suggested that increased ATG4C expression was associated with worse prognosis in glioma patients. Knockdown of ATG4C suppressed glioma progression by inducing cell cycle arrest and promoting apoptosis of glioma cells possibly through increasing production. | 31291988 |
| 2018-02-24 11:35:00 | association between SNPs and Kashin-Beck disease | 27742532 |
| 2017-10-14 10:28:00 | We demonstrate that, in breast cancer cells, ATM and ATG4C are essential drivers of mammosphere formation, suggesting that their targeting may improve current approaches to eradicate breast cancer cells with a stem-like phenotype. | 28423511 |
| Type | IDs |
|---|---|
| Synonymous | APG4-C, APG4C, AUTL1, AUTL3 |
| Gene |
UniProtKB-ID:
ATG4C_HUMAN,
A0A384MTY5_HUMAN
UniprotKB:
Q96DT6,
A0A384MTY5
UniParc:
UPI000000DC9F
EMBL:
BC033024,
AJ320169,
CH471059,
AJ312234,
AK027773,
GQ900993,
AC103923
Ensembl:
ENSG00000125703
KO:
hsa:84938
|
| Nucleutide sequences |
EMBL-CDS:
EAX06579.1,
CAC43939.1,
AAH33024.1,
BAB55356.1,
CAC85556.1,
EAX06580.1,
ADO22510.1
Ensembl_TRS:
ENST00000371120,
ENST00000317868
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360161,
ENSP00000322159
RefSeq:
XP_005271345.1,
XP_024306182.1,
XP_011540615.1,
XP_016858090.1,
XP_016858089.1,
NP_116241.2,
NP_835739.1
|
| Others |
UniRef100:
UniRef100_Q96DT6
UniRef90:
UniRef90_Q96DT6
UniRef50:
UniRef50_Q96DT6
UniGene:
Hs.7353
CCDS:
CCDS623.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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