| Type | Description |
|---|---|
| Definition | zinc and ring finger 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-16 10:40:00 | as a consequence of its high E2 affinity, an excess of ZNRF1 inhibits Ube2N-mediated ubiquitination at concentrations >/=500 nM instead of showing enhanced ubiquitination | 29626159 |
| 2016-03-12 10:18:00 | rs17684886 (ZNRF1) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes | 25819896 |
| 2013-04-27 10:38:00 | ZNRF1 and ZNRF2 are new players in regulation of the ubiquitous Na(+)/K(+)ATPase that is tuned to changing demands in many physiological contexts. | 22797923 |
| 2010-01-21 00:00:00 | data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity | 14561866 |
| 2010-01-21 00:00:00 | These results suggest that ZNRF1 mediates regulation of neuritogenesis via interaction with tubulin. | 19737534 |
| Type | IDs |
|---|---|
| Synonymous | NIN283 |
| Gene |
UniProtKB-ID:
ZNRF1_HUMAN
UniprotKB:
Q8ND25
UniParc:
UPI0000037DAA,
UPI00001FFC03
EMBL:
CH471114,
AF378524,
AC099508,
AL136903,
AL834440,
BC007235,
AC092383
Ensembl:
ENSG00000186187
KO:
hsa:84937
|
| Nucleutide sequences |
EMBL-CDS:
EAW95668.1,
CAB66837.1,
EAW95671.1,
AAH07235.1,
AAK69753.1,
CAD39100.1,
EAW95670.1
Ensembl_TRS:
ENST00000320619,
ENST00000567962,
ENST00000335325
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000323362,
ENSP00000455601,
ENSP00000335091
RefSeq:
XP_011521694.1,
XP_016879283.1,
XP_016879282.1,
NP_115644.1
|
| Others |
UniRef100:
UniRef100_Q8ND25
UniRef90:
UniRef90_Q8ND25
UniRef50:
UniRef50_Q8ND25
UniGene:
Hs.427284
CCDS:
CCDS10912.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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