| Type | Description |
|---|---|
| Definition | microtubule associated serine/threonine kinase like |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | MASTL promotes cell contractility and motility through kinase-independent signaling. | 32311005 |
| 2020-08-15 19:07:00 | AKT Regulates Mitotic Progression of Mammalian Cells by Phosphorylating MASTL, Leading to 2A Inactivation. | 32123010 |
| 2019-11-02 10:11:00 | MASTL depletion impaired thyroid tumor cell proliferation and increased the percentage of cells presenting nuclear anomalies, which are indicative of mitotic catastrophe. | 30445205 |
| 2019-09-21 12:14:00 | The proliferative function of MASTL in these tumor cells requires its kinase activity and the presence of PP2A-B55 complexes. | 29229993 |
| 2019-03-23 10:05:00 | Data show that MASTL expression increases in colon cancer (CC) across all cancer stages. Also, increased levels of MASTL associated with high-risk disease and poor prognosis. Further, its silencing induced cell cycle arrest and apoptosis in vitro and inhibited xenograft-tumor growth. Functional analysis revealed that MASTL expression facilitates CC progression and chemoresistance by promoting the beta-catenin/Wnt signa... | 30068336 |
| Type | IDs |
|---|---|
| Synonymous | GREATWALL, GW, GWL, MAST-L, THC2 |
| Gene |
UniProtKB-ID:
GWL_HUMAN
UniprotKB:
Q96GX5
UniParc:
UPI000004060D,
UPI000013D6AD,
UPI0000366674
EMBL:
AK027719,
AL160291,
AK074804,
BC009107
Ensembl:
ENSG00000120539
KO:
hsa:84930
|
| Nucleutide sequences |
EMBL-CDS:
BAC11218.1,
BAB55321.1,
AAH09107.1
Ensembl_TRS:
ENST00000375946,
ENST00000342386,
ENST00000375940
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343446,
ENSP00000365107,
ENSP00000365113
RefSeq:
XP_005252689.1,
NP_001165774.1,
NP_001165775.1,
XP_024304011.1,
NP_116233.2,
XP_016872341.1,
XP_016872344.1,
XP_016872342.1,
XP_006717583.1,
NP_001358959.1,
XP_011518053.1,
NP_001307685.1,
XP_024304012.1,
NP_001307686.1,
XP_005252688.1,
XP_016872345.1,
NP_001358958.1,
XP_006717582.1
|
| Others |
UniRef100:
UniRef100_Q96GX5
UniRef90:
UniRef90_Q96GX5
UniRef50:
UniRef50_Q96GX5
UniGene:
Hs.276905
CCDS:
CCDS53502.1,
CCDS7153.1,
CCDS53503.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员