| Type | Description |
|---|---|
| Definition | protein phosphatase, Mg2+/Mn2+ dependent 1D |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | Wip1 controls the translocation of the chromosomal passenger complex to the central spindle for faithful mitotic exit. | 33067654 |
| 2021-02-02 13:22:00 | WIP1 dephosphorylation of p27(Kip1) Serine 140 destabilizes p27(Kip1) and reverses anti-proliferative effects of ATM phosphorylation. | 31959038 |
| 2021-01-16 15:59:00 | PPM1D Functions as Oncogene and is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma. | 30374621 |
| 2021-01-16 15:57:00 | Wild-type p53-induced phosphatase 1 down-regulation promotes apoptosis by activating the DNA damage-response pathway in amyotrophic lateral sclerosis. | 31676238 |
| 2020-09-19 16:26:00 | Silencing of PPM1D inhibits cell proliferation and invasion through the p38 MAPK and p53 signaling pathway in papillary thyroid carcinoma. | 31922231 |
| Type | IDs |
|---|---|
| Synonymous | IDDGIP, PP2C-DELTA, WIP1 |
| Gene |
UniProtKB-ID:
PPM1D_HUMAN,
A0A0S2Z4M2_HUMAN
UniprotKB:
O15297,
A0A0S2Z4M2
UniParc:
UPI00000745DC,
UPI0000130FE8
EMBL:
CH471179,
BT009780,
KU178420,
AC011921,
U78305,
BC042418,
AC111155,
BC016480,
BC060877,
AC110602
Ensembl:
ENSG00000170836
KO:
hsa:8493
|
| Nucleutide sequences |
EMBL-CDS:
AAH16480.1,
AAH42418.1,
AAB61637.1,
EAW51409.1,
EAW51408.1,
AAP88782.1,
AAH60877.1,
ALQ33878.1
Ensembl_TRS:
ENST00000629650,
ENST00000392995,
ENST00000305921
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000306682,
ENSP00000376720,
ENSP00000486573
RefSeq:
NP_003611.1
|
| Others |
UniRef100:
UniRef100_O15297
UniRef90:
UniRef90_O15297
UniRef50:
UniRef50_O15297
UniGene:
Hs.286073
CCDS:
CCDS11625.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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