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84919 PPP1R15B

84919

PPP1R15B

protein phosphatase 1 regulatory subunit 15B

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein phosphatase 1 regulatory subunit 15B

研究结论

Date Results Publications
2019-05-04 12:16:00 p97-mediated degradation, together with a reduction in CReP synthesis, is essential for timely stress-induced reduction of CReP levels and, consequently, for robust eIF2alpha phosphorylation to enforce the stress response. 29599191
2016-09-17 11:38:00 Whole-exome sequencing identified a homozygous missense mutation, c.1972G>A; p.Arg658Cys, in protein phosphatase 1, regulatory subunit 15b (PPP1R15B) 26307080
2016-04-23 10:16:00 the first homozygous mutation in the PPP1R15B gene encoding the regulatory subunit of an eIF2alpha-specific phosphatase in two siblings affected by a novel syndrome of diabetes of youth with short stature, intellectual disability, and microcephaly 26159176
2016-02-19 14:00:00 CIP2A regulates cancer metabolism and CREB phosphorylation in non-small cell lung cancer 25325377
2013-01-05 10:55:00 the mammalian traffic machinery co-opts p-eIF2alpha and CReP, regulators of translation initiation. 22915583

名称对应

Type IDs
Synonymous CREP, MSSGM2
Gene
Nucleutide sequences
Protein sequencees
RefSeq: XP_005245608.2, NP_116222.4
Others
UniGene: Hs.304376

全选

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