| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Studying the Role and Molecular Mechanisms of MAP4K3 in Sorafenib Resistance of Hepatocellular Carcinoma. | 33204699 |
| 2020-05-30 13:09:00 | The GLK-induced AhR-ROR-gammat (and AhR-phosphorylated ROR-gammat) complex is a therapeutic target for the GLK(high)IL-17A(high) subpopulation of human patients with SLE. | 31318609 |
| 2020-05-30 12:06:00 | These findings show the critical role of the GLK-IQGAP cascade in cell migration and tumor metastasis | 31431460 |
| 2019-08-31 12:50:00 | MiR-206 contributed to euthyrox resistance in PTC cells through blockage p38 and JNK signaling pathway by targeting MAP4K3. | 30904818 |
| 2018-03-31 10:37:00 | MAP4K3 is identified as an amino acid-dependent regulator of autophagy through its phosphorylation of transcription factor EB (TFEB), a transcriptional activator of autophagy. | 29507340 |
| Type | IDs |
|---|---|
| Synonymous | GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1 |
| Gene |
UniProtKB-ID:
M4K3_HUMAN,
B3KMM5_HUMAN,
A8K602_HUMAN
UniprotKB:
Q8IVH8,
B3KMM5,
A8K602
UniParc:
UPI000002A172,
UPI000015F436,
UPI00015DA81B,
UPI000002A171,
UPI00000747E6
EMBL:
AF445390,
AF445402,
AF445398,
AF445397,
AF445401,
AF445406,
AK021553,
AF445405,
AC007684,
CH471053,
AF445404,
AF445399,
AF445386,
AF445394,
AF445411,
AF000145,
AF445407,
AF445409,
AF445392,
AK291467,
AF445396,
AF445412,
AF445385,
AF445395,
BC071579,
AF445387,
AF445413,
AF445391,
AF445400,
AF445388,
AF445408,
AF445393,
AF445410,
AF445403
Ensembl:
ENSG00000011566
KO:
hsa:8491
|
| Nucleutide sequences |
EMBL-CDS:
AAF19240.1,
AAH71579.1,
AAN75849.1,
EAX00346.1,
AAC15472.1,
AAN75850.1,
BAG51037.1,
BAF84156.1
Ensembl_TRS:
ENST00000341681,
ENST00000263881
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000345434,
ENSP00000263881
RefSeq:
XP_024308951.1,
NP_003609.2,
NP_001257354.1
|
| Others |
UniRef100:
UniRef100_B3KMM5,
UniRef100_Q8IVH8,
UniRef100_A8K602
UniRef90:
UniRef90_Q8IVH8,
UniRef90_A0A5E4BPP0
UniRef50:
UniRef50_Q8IVH8
UniGene:
Hs.655750
CCDS:
CCDS58707.1,
CCDS1803.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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