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84901 NFATC2IP

84901

NFATC2IP

nuclear factor of activated T cells 2 interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition nuclear factor of activated T cells 2 interacting protein

研究结论

Date Results Publications
2020-10-31 13:12:00 Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2). 31666531
2019-02-09 10:20:00 interactions of fat intake with the genetic (rs11150675) and transcriptional (ILMN_1725441) variations at the NFATC2IP locus on 2-year weight change. cis-DNA methylation at cg26663590 of the NFATC2IP locus showed an opposite impact on weight-loss in response to high-fat vs low-fat diet. baseline methylation at cg26663590 causally mediated 52.8% of the effect of rs11150675 on 2-year weight-loss in the high-fat diet group 29693310
2010-08-09 12:03:00 ZBTB25 functions as a negative regulator of nuclear factor of activated T cells (NF-AT) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes. 20410506

名称对应

Type IDs
Synonymous ESC2, NIP45, RAD60
Gene
UniProtKB-ID: NF2IP_HUMAN
UniprotKB: Q8NCF5
UniParc: UPI0000350B73, UPI0000072414, UPI00000316E2
EMBL: BC080628, AK027545, BC112182, AF458593, AK074761, AK316535, BC018311, BC101741, AK297333, BC068007, BC021551
Ensembl: ENSG00000176953
KO: hsa:84901
Nucleutide sequences
EMBL-CDS: AAH68007.1, AAH21551.2, AAH80628.1, AAI01742.1, BAC11189.1, BAH14906.1, AAI12183.1, AAM49721.1, BAB55189.1, BAH12551.1, AAH18311.2
Ensembl_TRS: ENST00000568148, ENST00000320805
Protein sequencees
Ensembl_PRO: ENSP00000324792, ENSP00000454958
RefSeq: NP_116204.3
Others
UniRef100: UniRef100_Q8NCF5
UniRef90: UniRef90_Q8NCF5
UniRef50: UniRef50_Q8NCF5
UniGene: Hs.513470
CCDS: CCDS10645.1

全选

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