| Type | Description |
|---|---|
| Definition | F-box DNA helicase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-24 10:35:00 | Report a requirement for in stabilizing replication forks that encounter base excision repair (BER) intermediates through Fbh1-dependent regulation of Rad51. Whereas Pduanyu372 is dispensable for tolerance of cells to single stranded breaks or homologous recombination dysfunction, it is redundant with in BER. | 29467415 |
| 2018-02-24 11:36:00 | study does not provide evidence for the contribution of rare non-synonymous FBXO18 variations to the genetic etiol - ogy of schizophrenia in the Japanese population. | 28317220 |
| 2016-02-13 11:48:00 | FBH1 acts as a negative regulator of RAD51 function in human cells | 25585578 |
| 2014-02-08 11:15:00 | FBH1 restraining RAD51 DNA binding under unperturbed growth conditions to prevent unwanted or unscheduled DNA recombination. | 24108124 |
| 2013-10-26 10:15:00 | FBH1 inactivation appears to contribute to oncogenic transformation by allowing survival of cells undergoing replicative stress due to external factors such as UV irradiation. | 23466708 |
| Type | IDs |
|---|---|
| Synonymous | FBXO18, Fbx18, hFBH1 |
| Gene |
UniProtKB-ID:
FBH1_HUMAN,
B3KV95_HUMAN,
F6UZG9_HUMAN,
Q2TAK1_HUMAN
UniprotKB:
Q8NFZ0,
B3KV95,
F6UZG9,
Q2TAK1
UniParc:
UPI000006EA63,
UPI000019AB6F,
UPI000019AB70,
UPI0000228856,
UPI000178E00D
EMBL:
AK095343,
BC012762,
AF456237,
AL137186,
AK027381,
BC032674,
BC110884,
AK122753,
AF454502,
CH471072,
AK315173,
AL133069,
AK027496,
AF380349,
BC113377
Ensembl:
ENSG00000134452
KO:
hsa:84893
|
| Nucleutide sequences |
EMBL-CDS:
AAH12762.2,
BAB55073.1,
CAB61392.1,
AAM73631.1,
AAI13378.1,
BAB55154.1,
AAP97705.1,
AAH32674.2,
EAW86426.1,
BAC04535.1,
AAP97700.1,
BAG53707.1,
EAW86425.1,
AAI10885.1,
EAW86427.1,
BAG37614.1
Gene_ORFName:
hCG_24070,
hCG_24070
Ensembl_TRS:
ENST00000379999,
ENST00000362091,
ENST00000397269
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369335,
ENSP00000355415,
ENSP00000380439
RefSeq:
XP_024304008.1,
XP_016872331.1,
NP_835363.1,
XP_016872335.1,
XP_016872333.1,
XP_024304009.1,
NP_001245381.1,
XP_016872334.1,
XP_016872332.1,
NP_001245382.1,
NP_116196.3,
XP_011518050.1
|
| Others |
UniRef100:
UniRef100_F6UZG9,
UniRef100_Q8NFZ0
UniRef90:
UniRef90_Q8NFZ0
UniRef50:
UniRef50_Q8NFZ0
UniGene:
Hs.498543
CCDS:
CCDS7073.1,
CCDS7072.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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