| Type | Description |
|---|---|
| Definition | apoptosis inducing factor mitochondria associated 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:03:00 | AIFM2 blocks ferroptosis independent of ubiquinol metabolism. | 31964528 |
| 2020-04-18 12:15:00 | identify FSP1 (previously known as AIFM2) as a key component of a non-mitochondrial CoQ antioxidant system that acts in parallel to the canonical glutathione-based GPX4 pathway | 31634900 |
| 2020-04-18 12:15:00 | AIFM2 (FSP1) confers protection against ferroptosis elicited by GPX4 deletion | 31634899 |
| 2019-06-08 11:59:00 | AIF-2 was upregulated in human glioma tissues and cell lines. Downregulation of AIF-2 reduced cell proliferation and induced G1 cell cycle arrest. | 30982162 |
| 2018-07-21 11:27:00 | Low AIFM2 expression is associated with T-cell lymphoblastic lymphoma. | 28534937 |
| Type | IDs |
|---|---|
| Synonymous | AMID, PRG3 |
| Gene |
UniProtKB-ID:
FSP1_HUMAN
UniprotKB:
Q9BRQ8
UniParc:
UPI0000D7A458,
UPI000003F07F
EMBL:
BC023601,
AL731540,
BC006121,
AF506757,
CH471083,
AF337957,
AK127353,
BX537621,
AK027403
Ensembl:
ENSG00000042286
KO:
hsa:84883
|
| Nucleutide sequences |
EMBL-CDS:
BAG54492.1,
AAL73229.1,
AAH23601.1,
CAH56481.1,
AAH06121.1,
AAM77596.1,
EAW54376.1,
BAB55089.1
Ensembl_TRS:
ENST00000373248,
ENST00000307864,
ENST00000613322
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000312370,
ENSP00000478931,
ENSP00000362345
RefSeq:
NP_116186.1,
NP_001185625.1
|
| Others |
UniRef100:
UniRef100_Q9BRQ8
UniRef90:
UniRef90_Q9BRQ8
UniRef50:
UniRef50_Q9BRQ8
UniGene:
Hs.650680
CCDS:
CCDS7297.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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