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84875 PARP10

84875

PARP10

poly(ADP-ribose) polymerase family member 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition poly(ADP-ribose) polymerase family member 10

研究结论

Date Results Publications
2020-12-12 13:25:00 PLK1/NF-kappaB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of and facilitates HCC progression. 32060423
2020-08-22 15:26:00 Influences the Proliferation of Colorectal Carcinoma Cells, a Preliminary Study]. 32392194
2019-07-13 11:24:00 promotes cellular proliferation, and its overexpression alleviates cellular sensitivity to replication stress and fosters the restart of stalled replication forks. In mouse xenograft studies, Pduanyu3710 loss reduces the tumorigenesis activity of HeLa cells. Its overexpression results in tumor formation by non-transformed RPE-1 cells. Pduanyu3710 may promote cellular transformation by alleviating replication stress. 30032250
2019-02-23 10:40:00 Study shows that is downregulated in intrahepatic metastatic hepatocellular carcinoma. Further results provide evidence that deficiency of Pduanyu3710 markedly increased the migration and invasion of tumor cells through regulation of epithelial-mesenchymal transition, and that Pduanyu3710 expression inhibited tumor metastasis in vivo. 29515234
2018-02-17 11:51:00 expression decreased upon fasting, a condition that is characterized by increases in mitochondrial biogenesis. Finally, lower Pduanyu3710 expression is associated with increased fatty acid oxidation 29293500

名称对应

Type IDs
Synonymous ARTD10
Gene
UniProtKB-ID: PAR10_HUMAN, E9PNI7_HUMAN, E9PK67_HUMAN, B4E0C4_HUMAN
UniprotKB: Q53GL7, E9PNI7, E9PK67, B4E0C4
UniParc: UPI0000251FAB, UPI0000E5AF99, UPI00017A8495, UPI0001F77E70
EMBL: BC019030, AC206437, BC014229, AK075250, AK303317, AK222914, AK027370, AC109322
Ensembl: ENSG00000178685
KO: hsa:84875
Nucleutide sequences
EMBL-CDS: BAB55067.1, BAC11498.1, AAH19030.2, BAD96634.1, AAH14229.2, BAG64386.1
Ensembl_TRS: ENST00000313028, ENST00000525773, ENST00000524918
Protein sequencees
Ensembl_PRO: ENSP00000325618, ENSP00000434776, ENSP00000431620
RefSeq: XP_011515638.1, NP_116178.2, NP_001304824.1
Others
UniRef100: UniRef100_E9PK67, UniRef100_Q53GL7, UniRef100_E9PNI7, UniRef100_B4E0C4
UniRef90: UniRef90_Q53GL7
UniRef50: UniRef50_Q53GL7
UniGene: Hs.348609
CCDS: CCDS34960.1

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