| Type | Description |
|---|---|
| Definition | gem nuclear organelle associated protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:35:00 | Here we show, using crystallographic and biochemical approaches, that Gemin2 of the SMN complex enhances RNA specificity of SmD1/D2/F/E/G via a negative cooperativity between Gemin2 and RNA in binding SmD1/D2/F/E/G. | 31799625 |
| 2017-09-09 11:40:00 | Specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of human Gemin2. | 27974620 |
| 2016-07-30 11:27:00 | The authors propose that Gemin2 is a versatile hub for ribonucleoprotein exchange that functions broadly in RNA metabolism. | 26828962 |
| 2015-12-12 10:55:00 | investigate the oligomeric nature of the SMN.Gemin2 complexes from humans and fission yeast (hSMN.Gemin2 and ySMN.Gemin2) | 26092730 |
| 2013-11-16 11:52:00 | Two monoclonal antibodies against SMN (survival-of-motor-neurons) protein bind to its site of interaction with gemin2. | 23939045 |
| Type | IDs |
|---|---|
| Synonymous | SIP1, SIP1-delta |
| Gene |
UniProtKB-ID:
GEMI2_HUMAN
UniprotKB:
O14893
UniParc:
UPI00000467E5,
UPI0000070115,
UPI000007358A,
UPI000012B3B7
EMBL:
AB037703,
AJ250933,
AJ250936,
AJ250939,
AF027150,
AB037702,
AJ250934,
BC104968,
AK313947,
AJ250938,
AJ250935,
AJ250932,
AJ250937,
AB037701
Ensembl:
ENSG00000092208
KO:
hsa:8487
|
| Nucleutide sequences |
EMBL-CDS:
BAB03509.1,
BAG36665.1,
BAB03510.1,
BAB03508.1,
AAB82297.1,
AAI04969.1,
CAC16117.2
Ensembl_TRS:
ENST00000412033,
ENST00000396249,
ENST00000250379,
ENST00000308317
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379548,
ENSP00000416827,
ENSP00000308533,
ENSP00000250379
RefSeq:
XP_016877198.1,
NP_001009182.2,
XP_024305499.1,
NP_001009183.2,
NP_003607.2
|
| Others |
UniRef100:
UniRef100_O14893
UniRef90:
UniRef90_O14893
UniRef50:
UniRef50_O14893
UniGene:
Hs.652307
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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