| Type | Description |
|---|---|
| Definition | PHD finger protein 5A |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:46:00 | we validated that PHF5A played an oncogenic role via AS in LUAD and suggested that PHF5A might serve as a potential drug target with a promising anticancer therapeutic effect. | 30932358 |
| 2020-01-18 10:11:00 | Acetylation of PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing-mediated upregulation of KDM3A. | 31054974 |
| 2019-08-03 12:03:00 | Study identified PHD finger protein 5A (PHF5A) as a key splicing factor involved in breast cancer progression. PHF5A expression was frequently upregulated in breast cancer and correlated with poor survival, and knockdown of PHF5A significantly suppressed cell proliferation, migration, and tumor formation. PHF5A was required for SF3b spliceosome stability and linked the complex to histones. | 29700004 |
| 2019-06-01 13:03:00 | PHF5A plays an indispensable role in progressive effect of NF-kappaB pathway in HCC. | 30766880 |
| 2019-05-11 10:56:00 | The data suggest for the first time that PHF5A is an oncoprotein that contributes to LAC progression by regulating multiple signaling pathways, and may constitute a prognostic factor and potential new therapeutic target in NSCLC. | 29566713 |
| Type | IDs |
|---|---|
| Synonymous | INI, Rds3, SAP14b, SF3B7, SF3b14b, bK223H9.2 |
| Gene |
UniProtKB-ID:
PHF5A_HUMAN,
A0A024R1U2_HUMAN
UniprotKB:
Q7RTV0,
A0A024R1U2
UniParc:
UPI000000110B
EMBL:
BC075808,
CR456398,
BC007321,
AL008582,
BK000563,
CH471095
Ensembl:
ENSG00000100410
KO:
hsa:84844
|
| Nucleutide sequences |
EMBL-CDS:
AAH07321.1,
CAG30284.1,
AAH75808.1,
DAA00074.1,
EAW60433.1,
EAW60434.1
Gene_ORFName:
hCG_41557
Ensembl_TRS:
ENST00000216252
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216252
RefSeq:
NP_116147.1
|
| Others |
UniRef100:
UniRef100_Q7RTV0
UniRef90:
UniRef90_Q7RTV0
UniRef50:
UniRef50_Q7RTV0
UniGene:
Hs.474980,
Hs.707800
CCDS:
CCDS14016.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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