| Type | Description |
|---|---|
| Definition | lamin B2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:54:00 | Lamin B2 promotes the malignant phenotype of non-small cell lung cancer cells by upregulating dimethylation of histone 3 lysine 9. | 32416090 |
| 2017-11-25 14:05:00 | our studies strongly implicate an overarching role for Lamin B2 in the maintenance of nuclear architecture since loss of Lamin B2 relieves the spatial positional constraints required for maintaining conserved localization of aneuploid chromosome territories in the interphase nucleus. | 26921073 |
| 2016-04-09 10:38:00 | Mutation of the nuclear lamin gene LMNB2 in progressive myoclonus epilepsy with early ataxia. | 25954030 |
| 2015-11-21 11:23:00 | Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform. | 25477337 |
| 2013-09-28 11:20:00 | Treating normal human fibroblasts with farnesyltransferase inhibitors causes the accumulation of unprocessed lamin B2 and lamin A and a decrease in mature lamin B1 | 23475125 |
| Type | IDs |
|---|---|
| Synonymous | EPM9, LAMB2, LMN2 |
| Gene |
UniProtKB-ID:
LMNB2_HUMAN
UniprotKB:
Q03252
UniParc:
UPI000059D625
EMBL:
M94362,
M94363,
BT007441,
AC011522,
BC006551,
AC005624
Ensembl:
ENSG00000176619
KO:
hsa:84823
|
| Nucleutide sequences |
EMBL-CDS:
AAH06551.1,
AAB00873.1,
AAP36109.1,
AAA80979.1,
AAC34573.1
Ensembl_TRS:
ENST00000325327
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327054
RefSeq:
NP_116126.3
|
| Others |
UniRef100:
UniRef100_Q03252
UniRef90:
UniRef90_Q03252
UniRef50:
UniRef50_Q03252
UniGene:
Hs.538286
CCDS:
CCDS12090.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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