| Type | Description |
|---|---|
| Definition | lysine methyltransferase 5C |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:28:00 | H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells. | 33144397 |
| 2018-12-22 11:22:00 | The analysis of human pancreatic cancer biopsies was concordant with these findings, because high levels of SUV420H2 correlated with a loss of epithelial characteristics in progressively invasive cancer. Together, these data indicate that SUV420H2 is an upstream epigenetic regulator of epithelial/mesenchymal state control. | 29229751 |
| 2017-11-26 01:40:00 | Study provides evidence that Suv420h2 controls the H4K20 methylome of osteoblasts and is critical for normal progression of osteoblastogenesis. | 27862226 |
| 2017-09-30 12:13:00 | Altogether, these results reveal Suv4-20h-mediated histone H4K20 tri-methylation as a critical determinant in the selection of active replication initiation sites in heterochromatin regions of mammalian genomes. | 28778956 |
| 2017-06-24 11:48:00 | The sequences surrounding both methylation sites do not fit to the specificity profile of SUV4-20H1. | 27105552 |
| Type | IDs |
|---|---|
| Synonymous | SUV420H2, Suv4-20h2 |
| Gene |
UniProtKB-ID:
KMT5C_HUMAN,
A0A0D9SF94_HUMAN
UniprotKB:
Q86Y97,
A0A0D9SF94
UniParc:
UPI00016111A5,
UPI000000DABC,
UPI0000070966
EMBL:
BC019313,
AF289582,
BC005842,
AC020922,
CH471135,
BC044889
Ensembl:
ENSG00000133247
KO:
hsa:84787
|
| Nucleutide sequences |
EMBL-CDS:
AAH05842.1,
AAH44889.1,
AAH19313.1,
AAL55766.1,
EAW72366.1
Gene_ORFName:
PP7130,
hCG_38236
Ensembl_TRS:
ENST00000255613,
ENST00000445196,
ENST00000592631,
ENST00000630497
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255613,
ENSP00000397296,
ENSP00000467499,
ENSP00000486397
RefSeq:
XP_005259395.1,
XP_006723505.1,
NP_116090.2,
XP_024307510.1,
XP_016882877.1,
XP_011525717.1
|
| Others |
UniRef100:
UniRef100_Q86Y97
UniRef90:
UniRef90_Q86Y97
UniRef50:
UniRef50_Q86Y97
UniGene:
Hs.590982
CCDS:
CCDS12922.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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