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84766 CRACR2A

84766

CRACR2A

calcium release activated channel regulator 2A

protein-coding

Homo sapiens

基因描述

Type Description
Definition calcium release activated channel regulator 2A

研究结论

Date Results Publications
2020-05-16 11:30:00 These data demonstrate for the first time that a Rab GTPase, Rab46, integrates G protein and Ca(2+) signals to couple on-demand histamine signals to selective Weibel-Palade bodies (WPBs) trafficking. 31092558
2020-04-18 10:51:00 Vigorous physical activity before diagnosis is associated with epigenetic alterations of CRACR2A and prostate cancer metastatic-lethal progression. 30464020
2019-03-16 10:57:00 There is a significant association between the EFCAB4B gene and localized periodontitis. 30284742
2017-11-11 10:22:00 Results show the characterization of CRACR2A protein which encodes a large Rab GTPase containing multiple functional domains contrary to small Rab GTPases. It was found to play an unexpected role in regulating intracellular signaling pathways important for T cell activation. 27221160
2016-12-17 10:58:00 GTP binding and prenylation of CRACR2A were associated with its localization near the Golgi and its stability 27016526

名称对应

Type IDs
Synonymous EFCAB4B
Gene
UniProtKB-ID: EFC4B_HUMAN
UniprotKB: Q9BSW2
UniParc: UPI00017A8807, UPI000006F61E
EMBL: AC006207, BC150643, AC005831, BC004524, AK304017
Ensembl: ENSG00000130038
KO: hsa:84766
Nucleutide sequences
EMBL-CDS: BAG64932.1, AAI50644.1, AAH04524.1
Ensembl_TRS: ENST00000252322, ENST00000440314
Protein sequencees
Ensembl_PRO: ENSP00000252322, ENSP00000409382
RefSeq: XP_011519340.1, NP_001138430.1, XP_006719084.1, XP_011519336.1, XP_011519339.1, NP_116069.1, XP_011519338.1
Others
UniRef100: UniRef100_Q9BSW2
UniRef90: UniRef90_Q9BSW2
UniRef50: UniRef50_Q9BSW2
UniGene: Hs.504534
CCDS: CCDS8522.1, CCDS44803.1

全选

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研究热度

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