| Type | Description |
|---|---|
| Definition | splA/ryanodine receptor domain and SOCS box containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 10:10:00 | Results demonstrated that cellular factor SPSB2 interacts with and decreases viral protein NS5A to inhibit HCV replication. SPSBP2 interacts with the HCV protein NS5A via its SPRY domain and inhibits HCV replication by ubiquitination and degradation of NS5A. | 31344133 |
| 2019-12-14 10:49:00 | C-terminal His6 tag of the recombinant protein binds to a shallow pocket adjacent to the iNOS-binding site on a crystallographically related SPSB2 molecule | 31204687 |
| 2017-09-30 12:12:00 | crystal structure of SPSB2 in complex with cyclic peptide inhibitor cR8, at a resolution of 1.34 A | 28549582 |
| 2009-09-22 21:00:00 | Shows that this gene is associated with the regulation of cell proliferation in canine mammary cancer cell lines. | 19609018 |
| Type | IDs |
|---|---|
| Synonymous | GRCC9, SSB2 |
| Gene |
UniProtKB-ID:
SPSB2_HUMAN
UniprotKB:
Q99619
UniParc:
UPI000003316E,
UPI0000493356
EMBL:
CH471116,
AK297963,
AF403027,
BC002983,
U47924,
BC071933
Ensembl:
ENSG00000111671
KO:
hsa:84727
|
| Nucleutide sequences |
EMBL-CDS:
AAL57346.1,
AAB51328.1,
EAW88720.1,
AAH02983.1,
EAW88719.1,
BAH12697.1,
AAH71933.1
Ensembl_TRS:
ENST00000523102,
ENST00000519357,
ENST00000524270
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000428338,
ENSP00000430872,
ENSP00000431037
RefSeq:
NP_116030.1,
NP_001306599.1,
NP_001139788.1
|
| Others |
UniRef100:
UniRef100_Q99619
UniRef90:
UniRef90_O88838
UniRef50:
UniRef50_O88838
UniGene:
Hs.479856
CCDS:
CCDS8567.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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