| Type | Description |
|---|---|
| Definition | insulin receptor substrate 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 10:56:00 | Mutations in IRS4 are associated with isolated congenital central hypothyroidism (CeH) in male carriers. As IRS4 is involved in leptin signalling, the phenotype may be related to disrupted leptin signalling. | 30061370 |
| 2019-08-24 12:18:00 | IRS4, as a new substrate of CHIP, is negatively regulated by CK1gamma2 at the posttranslational level. | 30026872 |
| 2018-08-18 10:51:00 | increase of IRS-4 expression may be involved to some extent in colorectal cancer. | 29185229 |
| 2017-09-09 11:55:00 | IRS4 overexpression is associated with cancer. | 27869826 |
| 2017-06-24 11:15:00 | these results demonstrated that miR-493 acts as a tumor suppressor and inhibits cell proliferation and cell cycle in human melanoma by directly targeting IRS4. | 28475006 |
| Type | IDs |
|---|---|
| Synonymous | IRS-4, PY160 |
| Gene |
UniProtKB-ID:
IRS4_HUMAN
UniprotKB:
O14654
UniParc:
UPI0000073FE7
EMBL:
CH471120,
AL035425,
AF007567
Ensembl:
ENSG00000133124
KO:
hsa:8471
|
| Nucleutide sequences |
EMBL-CDS:
AAC51738.1,
EAX02682.1
Ensembl_TRS:
ENST00000372129
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361202
RefSeq:
NP_003595.1,
XP_006724776.1,
XP_011529363.1,
NP_001366079.1
|
| Others |
UniRef100:
UniRef100_O14654
UniRef90:
UniRef90_O14654
UniRef50:
UniRef50_O14654
UniGene:
Hs.460872
CCDS:
CCDS14544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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