| Type | Description |
|---|---|
| Definition | ligand of numb-protein X 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 13:09:00 | Study reveals how the LNX1 RING domain is structurally and mechanistically dependent on other motifs for its E3 ligase activity, and describes how dimeric LNX1 recruits ubiquitin (Ub)-loaded Ubc13 for Ub transfer via E3 ligase-mediated catalysis. | 29496391 |
| 2017-12-30 10:50:00 | study provided the evidences that LNX1 signaling plays important roles in regulating the stemness of colon cancer cells | 29190716 |
| 2013-06-29 12:18:00 | LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch signaling. | 16324299 |
| 2013-03-02 11:45:00 | LNX1-mediated ubiquitination and degradation of PBK inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis. | 22889411 |
| 2012-05-19 10:47:00 | identify and confirm six novel LNX1 binding partners: KCNA4, PAK6, PLEKHG5, TYK2 and PBK, and suggest that LNX1 functions as a signalling scaffold. | 22087225 |
| Type | IDs |
|---|---|
| Synonymous | LNX, MPDZ, PDZRN2 |
| Gene |
UniProtKB-ID:
LNX1_HUMAN
UniprotKB:
Q8TBB1
UniParc:
UPI000012E7A6,
UPI000002AD5F
EMBL:
BC022983,
AC058822,
BC034737,
AF237782,
AY358326,
AK056823,
AC095040
Ensembl:
ENSG00000072201
KO:
hsa:84708
|
| Nucleutide sequences |
EMBL-CDS:
AAY41000.1,
AAK15039.1,
AAH34737.1,
AAH22983.1,
BAB71291.1,
AAQ88692.1
Gene_ORFName:
UNQ574/PRO1136
Ensembl_TRS:
ENST00000263925,
ENST00000306888
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000302879,
ENSP00000263925
RefSeq:
XP_024310030.1,
XP_024310029.1,
XP_016864265.1,
NP_116011.2,
XP_005265842.1,
NP_001119800.1
|
| Others |
UniRef100:
UniRef100_Q8TBB1
UniRef90:
UniRef90_Q8TBB1
UniRef50:
UniRef50_Q8TBB1
UniGene:
Hs.518760
CCDS:
CCDS47057.1,
CCDS3492.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Dana-Farber Cancer Institute |
9 |
| 2 |
University of Toronto |
9 |
| 3 |
Institute for Research in Biomedicine (IRB Barcelona) |
4 |
| 4 |
McGill University |
3 |
| 5 |
Whitehead Institute for Biomedical Research |
3 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
David E Hill |
10 |
| 2 |
Marc Vidal |
10 |
| 3 |
Tong Hao |
10 |
| 4 |
Frederick P Roth |
9 |
| 5 |
Michael A Calderwood |
7 |