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8467 SMARCA5

8467

SMARCA5

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

研究结论

Date Results Publications
2021-03-13 13:23:00 MiR-146b-5p suppresses the malignancy of GSC/MSC fusion cells by targeting SMARCA5. 32632040
2020-12-05 13:03:00 Loss of ISWI ATPase SMARCA5 (SNF2H) in Acute Myeloid Leukemia Cells Inhibits Proliferation and Chromatid Cohesion. 32197313
2020-05-02 10:46:00 A conserved basic motif within SNF2h that is essential for chromatinremodeling activity. 31819269
2020-02-29 10:47:00 Circ-SMARCA5 is downregulated and correlated with lower beta2-MG level and International Staging System stage as well as better prognosis in multiple myeloma patients, and it inhibits proliferation but promotes apoptosis of multiple myeloma cells via directly sponging miR-767-5p. 31601173
2020-02-22 13:04:00 Here, the authors show that the Chd1 remodeler from Saccharomyces cerevisiae and ISWI remodelers from human and Drosophila have distinct spatial requirements for the acidic patch. Unlike Chd1, which is equally affected by entry- and exit-side mutations, ISWI remodelers strongly depend on the entry-side acidic patch. 31094676

名称对应

Type IDs
Synonymous ISWI, SNF2H, WCRF135, hISWI, hSNF2H
Gene
UniProtKB-ID: SMCA5_HUMAN
UniprotKB: O60264
UniParc: UPI000006E693
EMBL: BC023144, AB010882
Ensembl: ENSG00000153147
KO: hsa:8467
Nucleutide sequences
EMBL-CDS: BAA25173.1, AAH23144.1
Ensembl_TRS: ENST00000283131
Protein sequencees
Ensembl_PRO: ENSP00000283131
RefSeq: NP_003592.3
Others
UniRef100: UniRef100_O60264
UniRef90: UniRef90_O60264
UniRef50: UniRef50_O60264
UniGene: Hs.558422
CCDS: CCDS3761.1

全选

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研究热度

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