| Type | Description |
|---|---|
| Definition | spermatogenic leucine zipper 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | SPZ1 promotes deregulation of Bim to boost apoptosis resistance in colorectal cancer. | 31934723 |
| 2019-05-11 13:07:00 | Tip60 mediates acetylation at lysine residues of SPZ1 at positions 369 and 374 which are required for SPZ1-TWIST1 complex formation and cancer cell migration in vitro and in vivo. | 30154425 |
| 2017-09-30 12:45:00 | SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. | 28368406 |
| 2010-01-21 00:00:00 | highly expressed in adult testis; may play an important role in spermatogenesis in the humans | 12778315 |
| Type | IDs |
|---|---|
| Synonymous | CILD38, NYD-TSP1, PPP1R148 |
| Gene |
UniProtKB-ID:
SPZ1_HUMAN,
A0A140VKA5_HUMAN
UniprotKB:
Q9BXG8,
A0A140VKA5
UniParc:
UPI000020CBA6
EMBL:
AF333098,
BC033798,
CH471084,
AC026410,
AK098575,
HM005645,
AK314007
Ensembl:
ENSG00000164299
KO:
hsa:84654
|
| Nucleutide sequences |
EMBL-CDS:
AAH33798.1,
BAG36718.1,
AAK17995.1,
EAW95848.1,
BAC05340.1,
AEE61242.1
Ensembl_TRS:
ENST00000296739
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369611
RefSeq:
NP_115956.3
|
| Others |
UniRef100:
UniRef100_Q9BXG8
UniRef90:
UniRef90_Q9BXG8
UniRef50:
UniRef50_Q9BXG8
UniGene:
Hs.519403
CCDS:
CCDS43336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31934723 |
SPZ1 promotes deregulation of Bim to boost apoptosis resistance in colorectal cancer. Clin Sci (Lond) Xiao-Yu Liu , Chang-Bo Zheng , Teng Wang , Jian Xu , Meng Zhang , Ling-Shan Gou , Linfang Jin , Xiaowei Qi , Xianhai Zeng , Hongwen Li , Shuqi Qiu , Peng Zhang |
2020-01-31 | - |
| 31515488 |
Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu |
2019-09-12 | - |
| 30154425 |
Oncogene Li-Ting Wang , Shen-Nien Wang , Shyh-Shin Chiou , Kwei-Yan Liu , Chee-Yin Chai , Cheng-Ming Chiang , Shau-Ku Huang , Kazunari K Yokoyama , Shih-Hsien Hsu |
2019-01-01 | - |
| 28368406 |
Oncogene L-T Wang , S-S Chiou , C-Y Chai , E Hsi , C-M Chiang , S-K Huang , S-N Wang , K K Yokoyama , S-H Hsu |
2017-08-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 23455924 |
A Y2H-seq approach defines the human protein methyltransferase interactome. Nat. Methods Mareike Weimann , Arndt Grossmann , Jonathan Woodsmith , Ziya Ãzkan , Petra Birth , David Meierhofer , Nouhad Benlasfer , Taras Valovka , Bernd Timmermann , Erich E Wanker , Sascha Sauer , Ulrich Stelzl |
2013-04-01 |
HMGXB4,
NR1H3,
AKAP9,
PRMT3,
SPRY2,
PRMT5,
MCRS1,
ECI2,
BAIAP2,
TADA3,
SYNCRIP,
CARM1,
BATF,
SLU7,
POLR3F,
MYL12A,
STARD10,
UTP14A,
MALT1,
SPIN1,
SF3B2,
NUDT21,
ATE1,
RASSF1,
RASSF8,
PMF1,
SNF8,
PNKP,
CDCA5,
OIP5,
LENG8,
HAUS1,
NOSTRIN,
CCDC151,
DNTTIP1,
RAB3IP,
SSX2IP,
CLK1,
CLK3,
ZNF641,
IKBIP,
AEBP2,
FRMD6,
CDYL2,
KRT222,
ZNF57,
GABPB2,
UBXN10,
TSACC,
ZNF280A,
NUDCD2,
ASB10,
VPS37A,
FOXR2,
ZFP28,
FAM76B,
ZNF480,
CCDC155,
C20orf196,
LCA5L,
SMYD1,
SPICE1,
FGD5,
SAMD3,
WBSCR27,
C8orf48,
AK8,
ADSS,
DYX1C1,
DAXX,
SPRED1,
C18orf54,
FAM9A,
DXO,
PHC2,
SPATA24,
C8orf74,
ETV3,
MECOM,
EWSR1,
EZH2,
JMJD1C,
ZUFSP,
MTF2,
CEP162,
BAHD1,
WDFY3,
KDM1A,
KDM4B,
SEPT6,
DIP2A,
MLC1,
JMJD6,
ITGB3BP,
BRD4,
TTC33,
ZKSCAN5,
STAC3,
FUS
|
| 21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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{{author.size}} |
目前还没有研究热点人员