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84632 AFAP1L2

84632

AFAP1L2

actin filament associated protein 1 like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition actin filament associated protein 1 like 2

研究结论

Date Results Publications
2020-07-11 12:33:00 High XB130 expression is associated with proliferation and metastasis of non-small-cell lung cancer. 32159887
2020-02-01 10:30:00 This study indicates that XB130 plays an important role in maintaining the epithelial-mesenchymal transition (EMT) and stem cell-like characteristics of breast cancer cells, supporting the significance of XB130 as a new potential therapeutic target for early diagnosis and prognosis of breast cancer. 31219645
2018-05-12 10:47:00 present study demonstrated that the expression of XB130 is elevated in CRC cells. Loss of XB130 was associated with decreased invasion and migration of CRC cells, possibly as a result of EMT inhibition. 28849225
2018-03-03 11:23:00 Our results suggest that dissociation between XB130 and Tks5 may facilitate lateral cell migration via XB130/Rac1, and vertical cell migration via Tks5/Cdc42. These molecular mechanisms will help our understanding of airway epithelial repair and regeneration. 27835612
2018-02-03 10:28:00 these observations suggest that XB130 may be a novel molecular marker and potent therapeutic target for prostate 27509056

名称对应

Type IDs
Synonymous CTB-1144G6.4, KIAA1914, XB130
Gene
UniProtKB-ID: AF1L2_HUMAN, B7Z2Q0_HUMAN
UniprotKB: Q8N4X5, B7Z2Q0
UniParc: UPI00004A22E0, UPI000052A459, UPI0001914B74, UPI0000071FAF, UPI00000709AB
EMBL: AB067501, AK027470, AL355302, AC005383, AF474151, AL133384, BC024314, AK123108, BC033212, AK291712, AK294969
Ensembl: ENSG00000169129
KO: hsa:84632
Nucleutide sequences
EMBL-CDS: BAB55135.1, AAQ05765.1, AAH33212.1, BAB67807.1, BAF84401.1, BAG53870.1, AAH24314.1, BAH11936.1
Ensembl_TRS: ENST00000304129, ENST00000369271
Protein sequencees
Ensembl_PRO: ENSP00000303042, ENSP00000358276
RefSeq: NP_001337997.1, NP_001338009.1, XP_016872303.1, NP_001338005.1, XP_016872319.1, NP_001337996.1, XP_016872307.1, NP_001337994.1, XP_016872287.1, XP_016872321.1, XP_016872284.1, XP_005270298.1, NP_001338007.1, NP_001337998.1, NP_001338008.1, NP_001337993.1, NP_001001936.1, NP_001337999.1, XP_005270294.1, NP_001338002.1, NP_115939.1, NP_001274753.1, XP_005270299.1, XP_016872318.1, XP_016872320.1, NP_001338000.1, NP_001338006.1, XP_016872285.1, XP_016872299.1, NP_001338001.1, XP_016872293.1, XP_005270290.1, NP_001338004.1, XP_016872286.1, NP_001337995.1, NP_001338003.1
Others
UniRef100: UniRef100_B7Z2Q0, UniRef100_Q8N4X5
UniRef90: UniRef90_Q8N4X5
UniRef50: UniRef50_Q8N4X5
UniGene: Hs.501106
CCDS: CCDS31287.1, CCDS31286.1

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研究热度

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