| Type | Description |
|---|---|
| Definition | par-6 family cell polarity regulator beta |
| Date | Results | Publications |
|---|---|---|
| 2018-05-19 11:37:00 | reduced expression of contributes to non-small-cell lung cancer epithelial-mesenchymal transition, invasion, and chemoresistance. | 28652146 |
| 2016-10-29 12:05:00 | found that the polarity determinants Cdc42, Par6B, and the structural proteins ezrin and phospho-ezrin were lost from the apical membrane and accumulated either in the cytoplasm or on the basal side of enterocytes in patients | 26526116 |
| 2015-06-20 12:37:00 | PAK4 phosphorylates Par6B at Ser143 blocking its interaction with Cdc42. | 25662318 |
| 2011-07-23 10:25:00 | Data conclude that Par6B and control mitotic spindle orientation in polarized epithelia and, furthermore, that aduanyu1531 coordinately regulates multiple processes to promote morphogenesis. | 21300793 |
| 2011-03-19 10:14:00 | This study demonstrates that controlled regulation of PAK4 is required for apical junction formation in lung epithelial cells and highlights potential cross-talk between two Cdc42 targets, PAK4 and Par6B. | 20631255 |
| Type | IDs |
|---|---|
| Synonymous | PAR6B |
| Gene |
UniProtKB-ID:
PAR6B_HUMAN
UniprotKB:
Q9BYG5
UniParc:
UPI0000E5A33E,
UPI000006FA7C
EMBL:
AB044555,
AB178534,
BC060847,
AL031680
Ensembl:
ENSG00000124171
KO:
hsa:84612
|
| Nucleutide sequences |
EMBL-CDS:
BAB40756.1,
AAH60847.1,
BAF92013.1
Ensembl_TRS:
ENST00000371610,
ENST00000396039
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379354,
ENSP00000360672
RefSeq:
NP_115910.1
|
| Others |
UniRef100:
UniRef100_Q9BYG5
UniRef90:
UniRef90_Q9BYG5
UniRef50:
UniRef50_Q9BYG5
UniGene:
Hs.589848
CCDS:
CCDS33485.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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