| Type | Description |
|---|---|
| Definition | Janus kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 10:53:00 | treatment downregulated the expression of JAK1, JAK3 and and upregulated cytosolic nuclear factor (NF)kappaB p65 and IkappaB. In conclusion, the results of the present study indicated that curculigoside exhibited significant antiarthritic effects in vivo and in vitro, and the molecular mechanism may be associated with the signaling pathway. | 30664158 |
| 2017-07-01 10:27:00 | Astrocyte expression of GLAST/GFAP was reduced via signaling pathway after exposure to sevoflurane. | 27003918 |
| 2015-12-05 10:49:00 | findings indicated that OSM induces Mcl-1 expression via activation of ERK1/2, JAK1/2, and CREB; furthermore, OSM-mediated Mcl-1 induction contributes to bioenergetic improvements | 25986861 |
| 2015-02-21 11:03:00 | These data demonstrate for the first time that KRV-induced islet destruction is associated with beta cell infection and intra-islet innate immune upregulation early in the disease process. | 25129435 |
| 2014-07-19 13:00:00 | Endogenous synthesis of IL-1beta is diminished in nerve tissue in type 1 diabetes and this defect triggers reduced signaling and mitochondrial function. | 24152426 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G3V9W2_RAT
UniprotKB:
G3V9W2
UniParc:
UPI0001551EF3
EMBL:
AABR07049385,
CH473998
Ensembl:
ENSRNOG00000011157
KO:
rno:84598
|
| Nucleutide sequences |
EMBL-CDS:
EDL97824.1
Gene_ORFName:
rCG_53517
Ensembl_TRS:
ENSRNOT00000064542
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000061649
RefSeq:
NP_445918.1,
XP_006238515.1,
XP_006238514.1
|
| Others |
UniRef100:
UniRef100_G3V9W2
UniRef90:
UniRef90_P52332
UniRef50:
UniRef50_P23458
UniGene:
Rn.90191
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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