| Type | Description |
|---|---|
| Definition | transcription termination factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | TTF2 is the only ATP-dependent termination activity associated with Pol II transcription elongation complexes, is largely unaffected by template position, and is impervious to the phosphorylation state of the polymerase. | 15125840 |
| 2010-01-21 00:00:00 | hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing | 12927788 |
| 2010-01-21 00:00:00 | Importantly, the mitotic phenotype seen with TTF2-siRNA is rescued by expression of the siRNA-resistant GFP-tagged TTF2 proving that reduced TTF2 is responsible for the retention of RNA polymerase II on mitotic chromosomes. | 15467445 |
| Type | IDs |
|---|---|
| Synonymous | HuF2, ZGRF6 |
| Gene |
UniProtKB-ID:
TTF2_HUMAN
UniprotKB:
Q9UNY4
UniParc:
UPI000013CCE7,
UPI000006E0D1
EMBL:
BC030058,
AL391476,
AL445231,
AK291017,
AF073771,
AF080255
Ensembl:
ENSG00000116830
KO:
hsa:8458
|
| Nucleutide sequences |
EMBL-CDS:
AAD49435.1,
BAF83706.1,
AAC64044.1,
AAH30058.1
Ensembl_TRS:
ENST00000369466
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358478
RefSeq:
XP_016858040.1,
XP_016858044.1,
XP_016858043.1,
XP_016858042.1,
XP_016858039.1,
XP_016858041.1,
XP_011540605.1,
NP_003585.3,
XP_005271334.1
|
| Others |
UniRef100:
UniRef100_Q9UNY4
UniRef90:
UniRef90_Q9UNY4
UniRef50:
UniRef50_Q9UNY4
UniGene:
Hs.486818
CCDS:
CCDS892.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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