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8453 CUL2

8453

CUL2

cullin 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition cullin 2

研究结论

Date Results Publications
2020-02-29 11:10:00 Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer 31898228
2019-08-31 10:06:00 Twist1 bound the Cul2 promoter. 29844124
2018-04-21 10:05:00 direct evidence that both A3A and HPV16 E7 interact with CUL2, suggesting that the E7-CUL2 complex formed during HPV infection may regulate A3A protein levels in the cell. 29367246
2018-03-24 11:20:00 The crystal structure of a pentameric CRL2(VHL) complex, composed of Cul2, Rbx1, Elongin B, Elongin C, and pVHL reveals hydrophobic contact residues critical for the Cul2 interactions. 28591624
2017-12-30 10:51:00 Results suggest that E7 recruited CUL2, driven by CUL2/E2F1/miR-424 regulatory loop, is overexpressed and accelerates HPV16-induced cervical carcinogenesis. 27153550

名称对应

Type IDs
Gene
UniProtKB-ID: CUL2_HUMAN, A0A140VKB1_HUMAN, A0A0A0MTN0_HUMAN, B7Z1Y1_HUMAN
UniprotKB: Q13617, A0A140VKB1, A0A0A0MTN0, B7Z1Y1
UniParc: UPI0000EE4467, UPI0001E92A29, UPI0001914D00, UPI0000000DC6
EMBL: U58088, AK300491, U83410, BC110901, AF126404, HM005651, CH471072, AK294080, AL392046, BC009591, AK095217
Ensembl: ENSG00000108094
KO: hsa:8453
Nucleutide sequences
EMBL-CDS: EAW85924.1, AAC51190.1, AAH09591.1, AAC50545.1, AAI10902.1, EAW85928.1, EAW85926.1, EAW85927.1, BAG53007.1, AAD23581.1, BAH13294.1, EAW85925.1, AEE61248.1, BAH11667.1
Ensembl_TRS: ENST00000673636, ENST00000374749, ENST00000421317, ENST00000374751, ENST00000374748, ENST00000537177
Protein sequencees
Ensembl_PRO: ENSP00000414095, ENSP00000363880, ENSP00000363883, ENSP00000363881, ENSP00000501215, ENSP00000444856
RefSeq: NP_001311305.1, NP_001185708.1, XP_011518046.1, NP_001311304.1, NP_003582.2, NP_001185707.1, NP_001185706.1, XP_011518045.1, XP_011518049.1, XP_011518047.1
Others
UniRef100: UniRef100_B7Z1Y1, UniRef100_A0A0A0MTN0, UniRef100_Q13617
UniRef90: UniRef90_Q13617
UniRef50: UniRef50_Q13617
UniGene: Hs.82919
CCDS: CCDS55709.1, CCDS7179.1

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