| Type | Description |
|---|---|
| Definition | HOP homeobox |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:59:00 | Molecular basis of the interaction of Hsp90 with its co-chaperone Hop. | 33040396 |
| 2021-01-02 12:52:00 | HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways. | 32647304 |
| 2020-06-20 10:52:00 | Study revealed that ZNF750 is both necessary and sufficient for HOPX induction and propose that HOPX functions as a positive regulator of epidermal late differentiation within a p63-ZNF750-HOPX pathway to up-regulate the key proteins required for terminal epidermal differentiation, providing clarity to previous studies showing conflicting results. | 30959041 |
| 2020-01-04 12:27:00 | These data indicated that miR421 may act as an oncogene through the effects of HOPX on the Wnt/bcatenin signaling pathway and may provide insight into the mechanisms underlying carcinogenesis and the identification of potential biomarkers associated with nonsmall cell lung cancer (NSCLC). | 31115507 |
| 2019-12-21 11:26:00 | In idiopathic pulmonary fibrosis lungs, HOPX expression was decreased in whole lungs and significantly correlated to a decline in lung function and progression of IPF. HOPX is upregulated during early alveolar injury and repair process in the lung. Decreased HOPX expression might contribute to failed regenerative processes in end-stage IPF lungs. | 30154568 |
| Type | IDs |
|---|---|
| Synonymous | CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO |
| Gene |
UniProtKB-ID:
HOP_HUMAN
UniprotKB:
Q9BPY8
UniParc:
UPI000004802F,
UPI000194EC25,
UPI000020B91A,
UPI000066D9ED
EMBL:
AF492676,
AF492679,
AF492677,
AF454763,
AB059408,
AF492681,
AF492678,
AF492680,
BC014225,
AF492675,
AC108215,
AB059410,
AK289707,
AB059409
Ensembl:
ENSG00000171476
KO:
hsa:84525
|
| Nucleutide sequences |
EMBL-CDS:
AAM46832.1,
BAB40926.1,
AAM46829.1,
AAM46830.1,
AAM46831.1,
AAH14225.1,
BAB40928.1,
AAL56613.1,
BAF82396.1,
AAM46828.1,
AAM46833.1,
BAB40927.1,
AAM46827.1
Ensembl_TRS:
ENST00000503639,
ENST00000317745,
ENST00000553379,
ENST00000381255,
ENST00000337881,
ENST00000508121,
ENST00000556614,
ENST00000556376,
ENST00000420433,
ENST00000555760,
ENST00000554144,
ENST00000381260
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000450527,
ENSP00000451794,
ENSP00000337330,
ENSP00000315198,
ENSP00000452340,
ENSP00000370659,
ENSP00000424101,
ENSP00000452098,
ENSP00000452003,
ENSP00000370654,
ENSP00000422175,
ENSP00000396275
RefSeq:
NP_115884.4,
XP_016864223.1,
NP_001138931.1,
XP_016864217.1,
NP_001138932.1,
XP_016864221.1,
XP_016864219.1,
XP_016864218.2,
XP_016864222.1,
NP_631958.1,
XP_016864220.1,
NP_631957.1,
XP_006714115.1
|
| Others |
UniRef100:
UniRef100_Q9BPY8
UniRef90:
UniRef90_Q9BPY8
UniRef50:
UniRef50_Q9BPY8
UniGene:
Hs.619396
CCDS:
CCDS3507.1,
CCDS54767.1,
CCDS47062.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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