| Type | Description |
|---|---|
| Definition | SET domain, bifurcated 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:11:00 | SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice. | 32360551 |
| 2021-01-09 13:26:00 | SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States. | 31914391 |
| 2020-11-21 13:29:00 | Hdac3, Setdb1, and Kap1 mark H3K9me3/H3K14ac bivalent regions in young and aged liver. | 31858687 |
| 2020-05-09 13:47:00 | found that levels of SETDB1 are decreased in patients with IBD, and that mice with reduced SETDB1 in intestinal stem cells developed spontaneous terminal ileitis and colitis | 32296174 |
| 2020-05-09 12:12:00 | Loss of SETDB1 disrupts telomeric heterochromatin and abrogates lengthening of telomeres. SETDB1 allows the recruitment of ATRX and histone chaperones to telomeric heterochromatin. | 31086817 |
| Type | IDs |
|---|---|
| Synonymous | AU022152, ESET, KMT1E, mKIAA0067 |
| Gene |
UniProtKB-ID:
D3YYC3_MOUSE,
G5E8N3_MOUSE
UniprotKB:
D3YYC3,
G5E8N3
UniParc:
UPI0000D6376C,
UPI000002140A
EMBL:
AC092202
Ensembl:
ENSMUSG00000015697
KO:
mmu:84505
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000107170,
ENSMUST00000015841,
ENSMUST00000107171
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015841,
ENSMUSP00000102788,
ENSMUSP00000102789
RefSeq:
XP_036019318.1,
NP_001157114.1,
NP_001157113.1,
NP_061365.3
|
| Others |
UniRef100:
UniRef100_G5E8N3,
UniRef100_D3YYC3
UniRef90:
UniRef90_O88974
UniRef50:
UniRef50_Q15047
UniGene:
Mm.490259
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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